methyl 23-benzyloxy-3α-hydroxyurs-12-en-28-oate

Base Information

Chemical Name:methyl 23-benzyloxy-3α-hydroxyurs-12-en-28-oate
CAS No.:303174-79-0
Molecular Formula:C₃₈H₅₆O₄
Molecular Weight:576.86
Hs Code.:

Synonyms:methyl 23-benzyloxy-3α-hydroxyurs-12-en-28-oate

Suppliers and Price of methyl 23-benzyloxy-3α-hydroxyurs-12-en-28-oate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 23-benzyloxy-3α-hydroxyurs-12-en-28-oate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 23-benzyloxy-3α-hydroxyurs-12-en-28-oate

There total 10 articles about methyl 23-benzyloxy-3α-hydroxyurs-12-en-28-oate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 303174-78-9
methyl 23-benzyloxy-3-oxours-12-en-28-oate

: 303174-79-0
methyl 23-benzyloxy-3α-hydroxyurs-12-en-28-oate

: methyl 23-benzyloxy-3β-hydroxyurs-12-en-28-oate

Guidance literature:: With aluminum isopropoxide; In isopropyl alcohol; for 10h; Heating;
DOI:10.1021/jo0008688

Reference yield:

: 77-52-1
ursolic acid

: 303174-79-0
methyl 23-benzyloxy-3α-hydroxyurs-12-en-28-oate

Guidance literature:: Multi-step reaction with 10 steps

1.1: diethyl ether; tetrahydrofuran

2.1: Jones / acetone

3.1: NH₂OH*HCl; NaOAc / methanol; CH₂Cl₂

4.1: Na₂PdCl₄; NaOAc / acetic acid / 72 h

4.2: DMAP; Et₃N / CH₂Cl₂ / 0.75 h / 20 °C

4.3: 1.92 g / Pb(OAc)4 / pyridine; tetrahydrofuran; acetic acid / 16 h / 20 °C

5.1: 98 percent / Na₂CO₃ / methanol / 16 h / 20 °C

6.1: 88 percent / 20percent HCl; NH₄OAc / TiCl₃ / H₂O; tetrahydrofuran / 4 h / 20 °C

7.1: 99 percent / PPTS; MS / benzene / 20 h / Heating

8.1: 94 percent / KH; n-Bu₄NI / tetrahydrofuran / 28 h / Heating

9.1: 91 percent / p-TsOH; PPTS / acetone / 48 h / 20 °C

10.1: 72 percent / Al(i-PrO)3 / propan-2-ol / 10 h / Heating

With sodium tetrachloropalladate(II); hydroxylamine hydrochloride; ammonium acetate; sodium acetate; pyridinium p-toluenesulfonate; aluminum isopropoxide; tetra-(n-butyl)ammonium iodide; potassium hydride; sodium carbonate; toluene-4-sulfonic acid; titanium(III) chloride; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; acetic acid; isopropyl alcohol; acetone; benzene; 1.1: Methylation / 2.1: Oxidation / 3.1: oximation / 4.1: complexation / 4.2: Acetylation / 4.3: Oxidation / 5.1: Deacetylation / 6.1: Oxidation / 7.1: Condensation / 8.1: Alkylation / 9.1: deacetalization / 10.1: Reduction;
DOI:10.1021/jo0008688

Reference yield:

: 915-32-2,26532-60-5,32208-45-0,74984-68-2,94482-47-0,121468-30-2
methyl (3β)-3-hydroxyurs-12-en-28-oate

: 303174-79-0
methyl 23-benzyloxy-3α-hydroxyurs-12-en-28-oate

Guidance literature:: Multi-step reaction with 9 steps

1.1: Jones / acetone

2.1: NH₂OH*HCl; NaOAc / methanol; CH₂Cl₂

3.1: Na₂PdCl₄; NaOAc / acetic acid / 72 h

3.2: DMAP; Et₃N / CH₂Cl₂ / 0.75 h / 20 °C

3.3: 1.92 g / Pb(OAc)4 / pyridine; tetrahydrofuran; acetic acid / 16 h / 20 °C

4.1: 98 percent / Na₂CO₃ / methanol / 16 h / 20 °C

5.1: 88 percent / 20percent HCl; NH₄OAc / TiCl₃ / H₂O; tetrahydrofuran / 4 h / 20 °C

6.1: 99 percent / PPTS; MS / benzene / 20 h / Heating

7.1: 94 percent / KH; n-Bu₄NI / tetrahydrofuran / 28 h / Heating

8.1: 91 percent / p-TsOH; PPTS / acetone / 48 h / 20 °C

9.1: 72 percent / Al(i-PrO)3 / propan-2-ol / 10 h / Heating

With sodium tetrachloropalladate(II); hydroxylamine hydrochloride; ammonium acetate; sodium acetate; pyridinium p-toluenesulfonate; aluminum isopropoxide; tetra-(n-butyl)ammonium iodide; potassium hydride; sodium carbonate; toluene-4-sulfonic acid; titanium(III) chloride; In tetrahydrofuran; methanol; dichloromethane; water; acetic acid; isopropyl alcohol; acetone; benzene; 1.1: Oxidation / 2.1: oximation / 3.1: complexation / 3.2: Acetylation / 3.3: Oxidation / 4.1: Deacetylation / 5.1: Oxidation / 6.1: Condensation / 7.1: Alkylation / 8.1: deacetalization / 9.1: Reduction;
DOI:10.1021/jo0008688