C-[3-(2-chloro-4-trifluoromethyl-phenyl)-5-(4-methoxy-phenyl)-3H-[1,2,3]triazol-4-yl]-methylamine

Base Information

Chemical Name:C-[3-(2-chloro-4-trifluoromethyl-phenyl)-5-(4-methoxy-phenyl)-3H-[1,2,3]triazol-4-yl]-methylamine
CAS No.:1207741-46-5
Molecular Formula:C₁₇H₁₄ClF₃N₄O
Molecular Weight:382.773
Hs Code.:

Synonyms:C-[3-(2-chloro-4-trifluoromethyl-phenyl)-5-(4-methoxy-phenyl)-3H-[1,2,3]triazol-4-yl]-methylamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C-[3-(2-chloro-4-trifluoromethyl-phenyl)-5-(4-methoxy-phenyl)-3H-[1,2,3]triazol-4-yl]-methylamine

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Technology Process of C-[3-(2-chloro-4-trifluoromethyl-phenyl)-5-(4-methoxy-phenyl)-3H-[1,2,3]triazol-4-yl]-methylamine

There total 1 articles about C-[3-(2-chloro-4-trifluoromethyl-phenyl)-5-(4-methoxy-phenyl)-3H-[1,2,3]triazol-4-yl]-methylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1207741-45-4
5-bromomethyl-1-(2-chloro-4-trifluoromethyl-phenyl)-4-(4-methoxy-phenyl)-1H-[1,2,3]triazole

: 1207741-46-5
C-[3-(2-chloro-4-trifluoromethyl-phenyl)-5-(4-methoxy-phenyl)-3H-[1,2,3]triazol-4-yl]-methylamine

Guidance literature:: With ammonia; In ethanol; at -20 ℃; for 0.416667h;

Reference yield: 69.0%

: 1207741-46-5
C-[3-(2-chloro-4-trifluoromethyl-phenyl)-5-(4-methoxy-phenyl)-3H-[1,2,3]triazol-4-yl]-methylamine

: 1207741-47-6
4-[5-aminomethyl-1-(2-chloro-4-trifluoromethyl-phenyl)-1H-[1,2,3]triazol-4-yl]-phenol

Guidance literature:: C-[3-(2-chloro-4-trifluoromethyl-phenyl)-5-(4-methoxy-phenyl)-3H-[1,2,3]triazol-4-yl]-methylamine; With boron tribromide; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

With methanol; water; In dichloromethane; Cooling with ice-salt bath;