N-α-({4-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-4-yl}carbonyl)-4-(2-methyl-1,1-dioxido-2,3-dihydro-1,2-benzisothiazol-5-yl)-L-phenylalaninamide

Base Information

Chemical Name:N-α-({4-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-4-yl}carbonyl)-4-(2-methyl-1,1-dioxido-2,3-dihydro-1,2-benzisothiazol-5-yl)-L-phenylalaninamide
CAS No.:1254319-25-9
Molecular Formula:C₂₈H₃₆N₄O₇S
Molecular Weight:572.682
Hs Code.:

N-α-({4-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-4-yl}carbonyl)-4-(2-methyl-1,1-dioxido-2,3-dihydro-1,2-benzisothiazol-5-yl)-L-phenylalaninamide

Synonyms:N-α-({4-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-4-yl}carbonyl)-4-(2-methyl-1,1-dioxido-2,3-dihydro-1,2-benzisothiazol-5-yl)-L-phenylalaninamide

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Chemical Property of N-α-({4-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-4-yl}carbonyl)-4-(2-methyl-1,1-dioxido-2,3-dihydro-1,2-benzisothiazol-5-yl)-L-phenylalaninamide

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Technology Process of N-α-({4-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-4-yl}carbonyl)-4-(2-methyl-1,1-dioxido-2,3-dihydro-1,2-benzisothiazol-5-yl)-L-phenylalaninamide

There total 1 articles about N-α-({4-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-4-yl}carbonyl)-4-(2-methyl-1,1-dioxido-2,3-dihydro-1,2-benzisothiazol-5-yl)-L-phenylalaninamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1254319-63-5
5-bromo-2-(methyl)-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide

: 1254319-24-8
(S)-tert-butyl-4-(1-amino-1-oxo-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-yl carbamoyl)tetrahydro-2H-pyran-4-yl carbamate

: 1254319-25-9
N-α-({4-[(tert-butoxycarbonyl)amino]tetrahydro-2H-pyran-4-yl}carbonyl)-4-(2-methyl-1,1-dioxido-2,3-dihydro-1,2-benzisothiazol-5-yl)-L-phenylalaninamide

Guidance literature:: 5-bromo-2-(methyl)-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide; (S)-tert-butyl-4-(1-amino-1-oxo-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-yl carbamoyl)tetrahydro-2H-pyran-4-yl carbamate; dichloro[1,1'-bis(di-t-butylphosphino)ferrocene]palladium(II); In acetonitrile; at 20 ℃; for 0.25h;

With potassium carbonate; In water; acetonitrile; at 80 ℃; for 7h;