1-phenyl-2-(N-2-chlorophenylpiperazinyl)acetyl-1,4-dihydro-3(2H)-isoquinolinone

Base Information

Chemical Name:1-phenyl-2-(N-2-chlorophenylpiperazinyl)acetyl-1,4-dihydro-3(2H)-isoquinolinone
CAS No.:133387-99-2
Molecular Formula:C₂₇H₂₆ClN₃O₂
Molecular Weight:459.975
Hs Code.:

Synonyms:1-phenyl-2-(N-2-chlorophenylpiperazinyl)acetyl-1,4-dihydro-3(2H)-isoquinolinone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-phenyl-2-(N-2-chlorophenylpiperazinyl)acetyl-1,4-dihydro-3(2H)-isoquinolinone

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Technology Process of 1-phenyl-2-(N-2-chlorophenylpiperazinyl)acetyl-1,4-dihydro-3(2H)-isoquinolinone

There total 2 articles about 1-phenyl-2-(N-2-chlorophenylpiperazinyl)acetyl-1,4-dihydro-3(2H)-isoquinolinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.6%

: 39512-50-0
N-(o-Chlorophenyl)piperazine

: 133387-96-9
1-phenyl-2-chloroacetyl-1,4-dihydro-3(2H)-isoquinolinone

: 133387-99-2
1-phenyl-2-(N-2-chlorophenylpiperazinyl)acetyl-1,4-dihydro-3(2H)-isoquinolinone

Guidance literature:: With sodium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 2.33333h;

Reference yield:

: 17507-05-0
1-phenyl-1,4-dihydro-3(2H)-isoquinolinone

: 133387-99-2
1-phenyl-2-(N-2-chlorophenylpiperazinyl)acetyl-1,4-dihydro-3(2H)-isoquinolinone

Guidance literature:: Multi-step reaction with 2 steps

1: 92.5 percent / benzene / 2 h / Heating

2: 54.6 percent / Na₂CO₃, KI / dimethylformamide / 2.33 h / 0 - 20 °C

With sodium carbonate; potassium iodide; In N,N-dimethyl-formamide; benzene;