1,5-anhydro-D-galactitol

Base Information

• Chemical Name: 1,5-anhydro-D-galactitol
• CAS No.: 3971-48-0
• Molecular Formula: C₆H₁₂O₅
• Molecular Weight: 164.158
• Mol file: 3971-48-0.mol

Synonyms:1,5-anhydro-D-galactitol

Chemical Property of 1,5-anhydro-D-galactitol

Chemical Property:

• Melting Point: 114-115 °C
• Boiling Point: 376.8±42.0 °C(Predicted)
• Density: 1.533±0.06 g/cm3(Predicted)

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,5-anhydro-D-galactitol

There total 16 articles about 1,5-anhydro-D-galactitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2,3,4,6-tetra-O-acetyl-1,5-anhydro-D-galactitol (13121-62-5) → 1,5-anhydro-D-galactitol (3971-48-0,53319-04-3)

Guidance literature:

With sodium methylate; In methanol; at 20 ℃; for 16h;

DOI:10.1016/j.carres.2008.03.017

Reference yield: 93.0%

C32H72O6Si4 → 1,5-anhydro-D-galactitol (3971-48-0,53319-04-3)

Guidance literature:

With triethylsilane; tris[3,5-bis(trifluoromethyl)phenyl]-borane; In dichloromethane; at 20 ℃; for 48h;

DOI:10.1021/acscatal.9b01578

Reference yield: 90.0%

N,N-diethyl β-D-galactopyranosyl dithiocarbamate (19200-39-6) → 1,5-anhydro-D-galactitol (3971-48-0,53319-04-3)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); hypophosphorous acid; sodium hydrogencarbonate; In ethanol; water; at 75 ℃; for 1h; Inert atmosphere;

DOI:10.1016/j.tetlet.2018.08.005

upstream raw materials:

2,3,4,6-tetra-O-acetyl-1,5-anhydro-D-galactitol

(2R,3S,4R,5S)-3,4,5-Tris-trimethylsilanyloxy-2-trimethylsilanyloxymethyl-tetrahydro-pyran

1,5-anhydro-3,4,6-tri-O-benzyl-D-galactitol

1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside

Downstream raw materials:

C₁₃H₁₆O₅

1,5-anhydro-6-O-tert-butyldiphenylsilyl-D-galactitol

1,5-Anhydro-2,6-di-O-benzyl-3,4-O-isopropylidene-D-galactitol

Methyl 1,5-di-O-benzyl-α-L-tagatopyranoside