Technology Process of S-3-(benzyloxycarbonylamino)-3-methylbutyl ethanethioate
There total 5 articles about S-3-(benzyloxycarbonylamino)-3-methylbutyl ethanethioate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sodium azide; acetic acid / water / 48 h / 95 °C
2: lithium aluminium tetrahydride / diethyl ether / 16 h / 0 - 25 °C
3: water; isopropyl alcohol / 16 h
4: methanesulfonyl chloride; triethylamine / dichloromethane / 2 h / 0 °C
5: N,N-dimethyl-formamide / 16 h / 20 - 70 °C
With
lithium aluminium tetrahydride; sodium azide; acetic acid; methanesulfonyl chloride; triethylamine;
In
diethyl ether; dichloromethane; water; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1016/j.bmcl.2011.04.084
- Guidance literature:
-
Multi-step reaction with 4 steps
1: lithium aluminium tetrahydride / diethyl ether / 16 h / 0 - 25 °C
2: water; isopropyl alcohol / 16 h
3: methanesulfonyl chloride; triethylamine / dichloromethane / 2 h / 0 °C
4: N,N-dimethyl-formamide / 16 h / 20 - 70 °C
With
lithium aluminium tetrahydride; methanesulfonyl chloride; triethylamine;
In
diethyl ether; dichloromethane; water; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1016/j.bmcl.2011.04.084
