1-(2-Furoyl)piperazine Hydrochloride

Base Information

• Chemical Name: 1-(2-Furoyl)piperazine Hydrochloride
• CAS No.: 60548-09-6
• Molecular Formula: C9H12N2O2^.HCl
• Molecular Weight: 216.66
• European Community (EC) Number: 677-536-2
• DSSTox Substance ID: DTXSID20484843
• Mol file: 60548-09-6.mol

Synonyms:60548-09-6;1-(2-Furoyl)piperazine Hydrochloride;furan-2-yl(piperazin-1-yl)methanone hydrochloride;1-(2-FUROYL)PIPERAZINE HCL;2-FURYL(1-PIPERAZINYL)METHANONE HYDROCHLORIDE;1-(2-Furanylcarbonyl)piperazine hydrochloride;1-(furan-2-carbonyl)piperazine hydrochloride;furan-2-yl(piperazin-1-yl)methanone;hydrochloride;SCHEMBL5204102;DTXSID20484843;FMFUHCXDFVDINI-UHFFFAOYSA-N;1-(2-Furanylcarbonyl)piperazine HCl;MFCD00236012;AKOS003744447;CS-W014829;SB60945;AS-10787;A8443;AM20100066;F0705;FT-0640698;EN300-36985;1-[(2-Furan)carbonyl]piperazine Hydrochloride;F17041;furan-2-yl(piperazin-1-yl)methanonehydrochloride;2-Furyl(1-piperazinyl)methanone hydrochloride (1:1);F3146-0171;Z111871202;1-(2-Furoyl)piperazine hydrochloride

Chemical Property of 1-(2-Furoyl)piperazine Hydrochloride

Chemical Property:

• Vapor Pressure: 3.15E-05mmHg at 25°C
• Melting Point: ?148°C(lit.)
• Boiling Point: 350.2 °C at 760 mmHg
• Flash Point: 165.6 °C
• PSA: 45.48000
• Density: 0.694g/mLat 25°C(lit.)
• LogP: 1.39370
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 216.0665554
• Heavy Atom Count: 14
• Complexity: 190

Purity/Quality:

99% ^*data from raw suppliers

1-(2-Furoyl)piperazine Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,Xn
• Hazard Codes: F,Xn

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CN(CCN1)C(=O)C2=CC=CO2.Cl

Technology Process of 1-(2-Furoyl)piperazine Hydrochloride

There total 1 articles about 1-(2-Furoyl)piperazine Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl 4-(furan-2-carbonyl)piperazine-1-carboxylate → N-(2-Furoyl)piperazine hydrochloride (60548-09-6)

Guidance literature:

Reference yield:

N-[4-(chloromethyl)-phenyl]-7-(4-methylphenyl)-3,4-dihydronaphthalene-2-carboxamide (229006-64-8) + N-(2-Furoyl)piperazine hydrochloride (60548-09-6) → N-[4-[1-(2-furoyl)-4-piperazinylmethyl]phenyl]-7-(4-methylphenyl)-3,4-dihydronaphthalene-2-carboxamide (229003-79-6)

Guidance literature:

With potassium carbonate; In water; N,N-dimethyl-formamide;

Downstream raw materials:

N-[4-[1-(2-furoyl)-4-piperazinylmethyl]phenyl]-7-(4-methylphenyl)-3,4-dihydronaphthalene-2-carboxamide

Refernces

• 1、 -. "2-, 3-, 4-, 5-, 6-, 7-, 8-, 9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use". . . Retrieved 2008/06/13.