(S)-Ginsenoside Rh2

Base Information

• Chemical Name: (S)-Ginsenoside Rh2
• CAS No.: 67400-17-3
• Molecular Formula: C₃₆H₆₂O₈
• Molecular Weight: 622.883
• Mol file: 67400-17-3.mol

Synonyms:Dammarane,a-D-glucopyranoside deriv.;

Chemical Property of (S)-Ginsenoside Rh2

Chemical Property:

• Boiling Point: 726.4 °C at 760 mmHg
• PKA: 12.91±0.70(Predicted)
• Flash Point: 393.1 °C
• PSA: 139.84000
• Density: 1.19 g/cm³
• LogP: 4.32480

Purity/Quality:

97% ^*data from raw suppliers

(S)-(3b,12b)-12,20-Dihydroxydammar-24-en-3-yl beta-D-glucopyranoside 90% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-Ginsenoside Rh2

There total 19 articles about (S)-Ginsenoside Rh2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3β-(2',3',4',6'-Tetra-O-acetyl-β-D-glucopyranosyloxy)-12β-acetoxydammar-24-en-20(S)-ol (127761-61-9) → Ginsenoside Rh2 (67400-17-3,78214-33-2,88156-29-0,112246-15-8,117708-91-5)

Guidance literature:

With sodium methylate; In methanol;

DOI:10.1007/BF00598267

Reference yield: 85.5%

β-cyclodextrin → ginsenoside Rh2 (67400-17-3,78214-33-2,88156-29-0,112246-15-8,117708-91-5)

Guidance literature:

With β-galactosidase from Aspergillus saponins; water; at 60 ℃; for 48h;

DOI:10.1039/c5ra11519a

Reference yield: 76.0%

C69H86O13 (873850-51-2) → ginsenoside Rh2 (67400-17-3,78214-33-2,88156-29-0,112246-15-8,117708-91-5)

Guidance literature:

With methanol; potassium hydroxide; at 20 ℃;

DOI:10.1016/j.tetlet.2011.04.003

upstream raw materials:

3β-(2',3',4',6'-Tetra-O-acetyl-β-D-glucopyranosyloxy)-12β-acetoxydammar-24-en-20(S)-ol

Betulafolienetriol

12β,20(S)-Dammar-24-en-3-one

12β-Acetoxy-20(S)-hydroxydammar-24-en-3-one

Downstream raw materials:

12,6'-dioctanoyl ginsenoside Rh₂

(3β,12β,20S)-12-(acetyloxy)-20-hydroxydammar-24(25)-en-3-yl β-D-glucopyranoside-2,3,4,6-tetraacetate

3,12-di-O-β-D-glucopyranosyl-dammar-24-ene-3β,12β,20(S)-triol