Benzyl (8-hydroxyoctyl)carbamate

Base Information

Chemical Name:Benzyl (8-hydroxyoctyl)carbamate
CAS No.:134477-39-7
Molecular Formula:C₁₆H₂₅NO₃
Molecular Weight:279.379
Hs Code.:
European Community (EC) Number:854-458-9

Synonyms:Benzyl (8-hydroxyoctyl)carbamate;134477-39-7;benzyl N-(8-hydroxyoctyl)carbamate;Benzyl(8-hydroxyoctyl)carbamate;SCHEMBL7037381;EN300-314686;A1-39703

Suppliers and Price of Benzyl (8-hydroxyoctyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Benzyl (8-hydroxyoctyl)carbamate

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:11
Exact Mass:279.18344366
Heavy Atom Count:20
Complexity:240

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC(=O)NCCCCCCCCO

Technology Process of Benzyl (8-hydroxyoctyl)carbamate

There total 6 articles about Benzyl (8-hydroxyoctyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 19008-71-0
8-aminooctan-1-ol

: 501-53-1,94274-21-2
benzyl chloroformate

: 134477-39-7
8-<(benzyloxycarbonyl)amino>octan-1-ol

Guidance literature:: With sodium hydrogencarbonate; In water; acetone; for 21h; Ambient temperature;
DOI:10.1021/jm00075a029

Reference yield: 37.0%

: methyl 8-(((benzyloxy)carbonyl)amino)octanoate

: 134477-39-7
8-<(benzyloxycarbonyl)amino>octan-1-ol

Guidance literature:: With diisobutylaluminium hydride; In dichloromethane; at 0 - 20 ℃; for 12h;
DOI:10.1016/j.bmcl.2014.09.081

Reference yield:

: 1002-57-9
8-Aminooctanoic acid

: 134477-39-7
8-<(benzyloxycarbonyl)amino>octan-1-ol

Guidance literature:: Multi-step reaction with 3 steps

1: acetyl chloride / 12 h / Reflux

2: sodium hydrogencarbonate / tetrahydrofuran; water / 12 h / -7 - 20 °C

3: diisobutylaluminium hydride / dichloromethane / 12 h / 0 - 20 °C

With diisobutylaluminium hydride; sodium hydrogencarbonate; acetyl chloride; In tetrahydrofuran; dichloromethane; water;
DOI:10.1016/j.bmcl.2014.09.081