(1S,3R,7R,8S,11S)-9-<(benzyloxy)carbonyl>-11-chloro-5,5-dimethyl-2,4,6-trioxa-9-azatricyclo<6.3.0.0^3,7>undecane

Base Information

• Chemical Name: (1S,3R,7R,8S,11S)-9-<(benzyloxy)carbonyl>-11-chloro-5,5-dimethyl-2,4,6-trioxa-9-azatricyclo<6.3.0.0^3,7>undecane
• CAS No.: 98944-19-5
• Molecular Formula: C₁₇H₂₀ClNO₅
• Molecular Weight: 353.803

Synonyms:(1S,3R,7R,8S,11S)-9-<(benzyloxy)carbonyl>-11-chloro-5,5-dimethyl-2,4,6-trioxa-9-azatricyclo<6.3.0.0^3,7>undecane

Chemical Property of (1S,3R,7R,8S,11S)-9-<(benzyloxy)carbonyl>-11-chloro-5,5-dimethyl-2,4,6-trioxa-9-azatricyclo<6.3.0.0^3,7>undecane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S,3R,7R,8S,11S)-9-<(benzyloxy)carbonyl>-11-chloro-5,5-dimethyl-2,4,6-trioxa-9-azatricyclo<6.3.0.0^3,7>undecane

There total 3 articles about (1S,3R,7R,8S,11S)-9-<(benzyloxy)carbonyl>-11-chloro-5,5-dimethyl-2,4,6-trioxa-9-azatricyclo<6.3.0.0^3,7>undecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(1S,3R,7R,8S,11R)-9-<(benzyloxy)carbonyl>-11-<(methylsulfonyl)oxy>-5,5-dimethyl-2,4,6-trioxa-9-azatricyclo<6.3.0.03,7>undecane (84730-22-3) → (1S,3R,7R,8S,11S)-9-<(benzyloxy)carbonyl>-11-chloro-5,5-dimethyl-2,4,6-trioxa-9-azatricyclo<6.3.0.03,7>undecane (98944-19-5)

Guidance literature:

With lithium chloride; In N,N-dimethyl-formamide; at 130 ℃; for 17h;

DOI:10.1021/jo00225a045

Reference yield:

3-azido-3-deoxy-1,2-O-isopropylidene-5,6-di-O-mesyl-α-D-glucofuranose (96625-41-1) → (1S,3R,7R,8S,11S)-9-<(benzyloxy)carbonyl>-11-chloro-5,5-dimethyl-2,4,6-trioxa-9-azatricyclo<6.3.0.03,7>undecane (98944-19-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 100 percent / H₂ / Raney Ni / ethyl acetate; methanol / 2 h

2: 100 percent / triethylamine / methanol / 2 h / Ambient temperature

3: 85 percent / LiCl / dimethylformamide / 17 h / 130 °C

With hydrogen; triethylamine; lithium chloride; nickel; In methanol; ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1021/jo00225a045

Reference yield:

(1S,3R,7R,8S,11R)-11-<(methylsulfonyl)oxy>-5,5-dimethyl-2,4,6-trioxa-9-azatricyclo<6.3.0.03,7>undecane (98944-18-4) → (1S,3R,7R,8S,11S)-9-<(benzyloxy)carbonyl>-11-chloro-5,5-dimethyl-2,4,6-trioxa-9-azatricyclo<6.3.0.03,7>undecane (98944-19-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / triethylamine / methanol / 2 h / Ambient temperature

2: 85 percent / LiCl / dimethylformamide / 17 h / 130 °C

With triethylamine; lithium chloride; In methanol; N,N-dimethyl-formamide;

DOI:10.1021/jo00225a045

upstream raw materials:

(1S,3R,7R,8S,11R)-9-<(benzyloxy)carbonyl>-11-<(methylsulfonyl)oxy>-5,5-dimethyl-2,4,6-trioxa-9-azatricyclo<6.3.0.0^3,7>undecane

3-azido-3-deoxy-1,2-O-isopropylidene-5,6-di-O-mesyl-α-D-glucofuranose

(1S,3R,7R,8S,11R)-11-<(methylsulfonyl)oxy>-5,5-dimethyl-2,4,6-trioxa-9-azatricyclo<6.3.0.0^3,7>undecane

Downstream raw materials:

(1R,3S,4R,5S)-4-(benzyloxy)-5-<(benzyloxy)carbonyl>-3-methoxy-2-oxa-6-azabicyclo<3.3.0>octane

(1R,3R,4R,5S)-4-(benzyloxy)-5-<(benzyloxy)carbonyl>-3-methoxy-2-oxa-6-azabicyclo<3.3.0>octane

(1R,3S,4R,5S)-5-<(benzyloxy)carbonyl>-3-methoxy-2-oxa-6-azabicyclo<3.3.0>octan-4-ol

(1R,3R,4R,5S)-5-<(benzyloxy)carbonyl>-3-methoxy-2-oxa-6-azabicyclo<3.3.0>octan-4-ol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 98944-19-5 (1S,3R,7R,8S,11S)-9-<(benzyloxy)carbonyl>-11-chloro-5,5-dimethyl-2,4,6-trioxa-9-azatricyclo<6.3.0.0^3,7>undecane

Send

Send

Metric Ton KG G Pound L ML

Send

Send