Technology Process of Formic acid (1S,4aS,8aS)-5,5,8a-trimethyl-2-methylene-decahydro-naphthalen-1-ylmethyl ester
There total 1 articles about Formic acid (1S,4aS,8aS)-5,5,8a-trimethyl-2-methylene-decahydro-naphthalen-1-ylmethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: KMnO4; MgSO4 / acetone / 20 °C
2: 66 percent / oxygen / 1,2-dimethoxy-ethane / 4 h / 20 °C
3: 95 percent / LiAlH4 / tetrahydrofuran / 2 h / Heating
4: 8 percent / molecular sieves 4 Angstroem; N-methylmorpholine N-oxide; tetra-n-propylammonium perruthenate / CH2Cl2
5: 94 percent / NaHCO3; m-chloroperbenzoic acid / CH2Cl2 / -78 °C
With
potassium permanganate; lithium aluminium tetrahydride; tetrapropylammonium perruthennate; 4 A molecular sieve; oxygen; sodium hydrogencarbonate; magnesium sulfate; 4-methylmorpholine N-oxide; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; 1,2-dimethoxyethane; dichloromethane; acetone;
5: Baeyer-Villiger oxidation;
DOI:10.1080/00397910500377172
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 95 percent / potassium hydroxide / methanol / 20 °C
2.1: 85 percent / molecular sieves 4 Angstroem; N-methylmorpholine N-oxide; tetra-n-propylammonium perruthenate / CH2Cl2
3.1: sec-butyllithium / hexane; tetrahydrofuran / 0 - 20 °C
3.2: 93 percent / hexane; tetrahydrofuran / 1 h
4.1: 94 percent / Li; liq. ammonia / tetrahydrofuran / 0.33 h / -78 °C
5.1: 94 percent / pyridinium p-toluenesulfonate / ethanol / 2 h / 20 °C
With
potassium hydroxide; tetrapropylammonium perruthennate; 4 A molecular sieve; ammonia; sec.-butyllithium; pyridinium p-toluenesulfonate; lithium; 4-methylmorpholine N-oxide;
In
tetrahydrofuran; methanol; ethanol; hexane; dichloromethane;
DOI:10.1080/00397910500377172
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 95 percent / potassium hydroxide / methanol / 20 °C
2.1: 85 percent / molecular sieves 4 Angstroem; N-methylmorpholine N-oxide; tetra-n-propylammonium perruthenate / CH2Cl2
3.1: sec-butyllithium / hexane; tetrahydrofuran / 0 - 20 °C
3.2: 93 percent / hexane; tetrahydrofuran / 1 h
4.1: 94 percent / Li; liq. ammonia / tetrahydrofuran / 0.33 h / -78 °C
With
potassium hydroxide; tetrapropylammonium perruthennate; 4 A molecular sieve; ammonia; sec.-butyllithium; lithium; 4-methylmorpholine N-oxide;
In
tetrahydrofuran; methanol; hexane; dichloromethane;
DOI:10.1080/00397910500377172
