2-(3-amino-4-hydroxyphenyl)-N-((4-chloro-2-methylphenyl)(phenyl)methyl)-2-methylpropanamide

Base Information

• Chemical Name: 2-(3-amino-4-hydroxyphenyl)-N-((4-chloro-2-methylphenyl)(phenyl)methyl)-2-methylpropanamide
• CAS No.: 1422169-81-0
• Molecular Formula: C₂₄H₂₅ClN₂O₂
• Molecular Weight: 408.928

Synonyms:2-(3-amino-4-hydroxyphenyl)-N-((4-chloro-2-methylphenyl)(phenyl)methyl)-2-methylpropanamide

Chemical Property of 2-(3-amino-4-hydroxyphenyl)-N-((4-chloro-2-methylphenyl)(phenyl)methyl)-2-methylpropanamide

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Technology Process of 2-(3-amino-4-hydroxyphenyl)-N-((4-chloro-2-methylphenyl)(phenyl)methyl)-2-methylpropanamide

There total 1 articles about 2-(3-amino-4-hydroxyphenyl)-N-((4-chloro-2-methylphenyl)(phenyl)methyl)-2-methylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-(3-amino-4-hydroxyphenyl)-N-((4-chloro-2-methylphenyl)(phenyl)methyl)-2-methylpropanamide (1422169-81-0)

Guidance literature:

With ammonium chloride; zinc; In ethanol; water; at 60 ℃; for 3h;

Reference yield: 93.0%

2-methylnicotinic acid (3222-56-8) + 2-(3-amino-4-hydroxyphenyl)-N-((4-chloro-2-methylphenyl)(phenyl)methyl)-2-methylpropanamide (1422169-81-0) → N-(5-(2-(((4-chloro-2-methylphenyl)(phenyl)methyl)amino)-2-oxoethyl)-2-hydroxyphenyl)-2-methylnicotinamide

Guidance literature:

2-methylnicotinic acid; With thionyl chloride; In dichloromethane; for 1h; Reflux;

2-(3-amino-4-hydroxyphenyl)-N-((4-chloro-2-methylphenyl)(phenyl)methyl)-2-methylpropanamide; With N-ethyl-N,N-diisopropylamine; In dichloromethane;

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