LDN-0064229

Base Information

• Chemical Name: LDN-0064229
• CAS No.: 38371-84-5
• Molecular Formula: C₁₃H₁₀N₂O₂
• Molecular Weight: 226.235
• Mol file: 38371-84-5.mol

Synonyms:LDN-0064229

Chemical Property of LDN-0064229

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of LDN-0064229

There total 10 articles about LDN-0064229 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

2-Furan-2-yl-5-oxa-3,3a-diaza-cyclopenta[a]naphthalen-4-one (153685-74-6) → LDN-0064229 (38371-84-5)

Guidance literature:

With potassium hydroxide; In 1,4-dioxane; at 70 ℃; for 6h;

DOI:10.1002/ardp.19933261012

Reference yield:

2-(5-Furan-2-yl-3,4-dihydro-2H-pyrazol-3-yl)-phenol → LDN-0064229 (38371-84-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 75 percent / NaH / toluene / 3 h

2: 70 percent / tetrachloro-o-benzoquinone / toluene / 1 h / Heating

3: 50 percent / 10percent aq. KOH / dioxane / 6 h / 70 °C

With potassium hydroxide; o-tetrachloroquinone; sodium hydride; In 1,4-dioxane; toluene;

DOI:10.1002/ardp.19933261012

Reference yield:

2-Furan-2-yl-1,9b-dihydro-5-oxa-3,3a-diaza-cyclopenta[a]naphthalen-4-one (153685-72-4) → LDN-0064229 (38371-84-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / tetrachloro-o-benzoquinone / toluene / 1 h / Heating

2: 50 percent / 10percent aq. KOH / dioxane / 6 h / 70 °C

With potassium hydroxide; o-tetrachloroquinone; In 1,4-dioxane; toluene;

DOI:10.1002/ardp.19933261012

upstream raw materials:

1-(2-hydroxyphenyl)-3-(furan-2-yl)propane-1,3-dione

5-(2-furyl)-4,5-dihydro-3-(2-hydroxyphenyl)pyrazole

2-furanoic acid

2-acetylphenyl furan-2-carboxylate