ethyl 2-<(4-bromophenyl)methyl>-2,3-dihydro-3-hydroxy-1,2-benzisothiazole-3-carboxylate 1,1-dioxide

Base Information

Chemical Name:ethyl 2-<(4-bromophenyl)methyl>-2,3-dihydro-3-hydroxy-1,2-benzisothiazole-3-carboxylate 1,1-dioxide
CAS No.:150256-96-5
Molecular Formula:C₁₇H₁₆BrNO₅S
Molecular Weight:426.288
Hs Code.:

Synonyms:ethyl 2-<(4-bromophenyl)methyl>-2,3-dihydro-3-hydroxy-1,2-benzisothiazole-3-carboxylate 1,1-dioxide

Suppliers and Price of ethyl 2-<(4-bromophenyl)methyl>-2,3-dihydro-3-hydroxy-1,2-benzisothiazole-3-carboxylate 1,1-dioxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 2-<(4-bromophenyl)methyl>-2,3-dihydro-3-hydroxy-1,2-benzisothiazole-3-carboxylate 1,1-dioxide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 2-<(4-bromophenyl)methyl>-2,3-dihydro-3-hydroxy-1,2-benzisothiazole-3-carboxylate 1,1-dioxide

There total 4 articles about ethyl 2-<(4-bromophenyl)methyl>-2,3-dihydro-3-hydroxy-1,2-benzisothiazole-3-carboxylate 1,1-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 109-72-8,29786-93-4
n-butyllithium

: 95-92-1
oxalic acid diethyl ester

: 150256-96-5
ethyl 2-<(4-bromophenyl)methyl>-2,3-dihydro-3-hydroxy-1,2-benzisothiazole-3-carboxylate 1,1-dioxide

Guidance literature:: In tetrahydrofuran; hexane; water; Petroleum ether;

Reference yield:

: 2905-25-1
o-bromobenzenesulfonyl chloride

: 150256-96-5
ethyl 2-<(4-bromophenyl)methyl>-2,3-dihydro-3-hydroxy-1,2-benzisothiazole-3-carboxylate 1,1-dioxide

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / pyridine, 4-dimethylaminopyridine, Et₃N / CH₂Cl₂ / Ambient temperature

2: 1.) NaH, 2.) BuLi

With pyridine; dmap; n-butyllithium; sodium hydride; triethylamine; In dichloromethane;
DOI:10.3987/COM-94-6750

Reference yield:

: 26177-44-6
4-bromobenzylamine hydrochloride

: 150256-96-5
ethyl 2-<(4-bromophenyl)methyl>-2,3-dihydro-3-hydroxy-1,2-benzisothiazole-3-carboxylate 1,1-dioxide

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / pyridine, 4-dimethylaminopyridine, Et₃N / CH₂Cl₂ / Ambient temperature

2: 1.) NaH, 2.) BuLi

With pyridine; dmap; n-butyllithium; sodium hydride; triethylamine; In dichloromethane;
DOI:10.3987/COM-94-6750