Ethyl 1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylate

Base Information

Chemical Name:Ethyl 1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylate
CAS No.:88398-81-6
Molecular Formula:C7H11N3O4S
Molecular Weight:233.248
Hs Code.:2935009090
DSSTox Substance ID:DTXSID40538357
Nikkaji Number:J319.682H
Wikidata:Q72442074
Mol file:88398-81-6.mol

Synonyms:88398-81-6;Ethyl 1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylate;88398-83-8;Ethyl 1-methyl-5-sulfamoylpyrazole-4-carboxylate;1-methyl-4-ethyl formate-5-pyrazole sulfonamide;1-methyl-5-sulfamoyl-4-pyrazolecarboxylic acid ethyl ester;1H-Pyrazole-4-carboxylic acid, 5-(aminosulfonyl)-1-methyl-, methylester;1-Methyl-4-ethylformate-5-pyrazole sulfonamide;5-(aminosulfonyl)-1-methyl-1h-pyrazole-4-carboxylic acid ethyl ester;ethyl 1-methyl-5-sulfamoyl-pyrazole-4-carboxylate;5-(Aminosulfonyl)-1-Methyl-1H- Pyrazole-4-Carbo;1-Methyl-4-ethoxycarbonylpyrazole-5-sulfonamide;1-methyl-4-ethy1 formate-5-pyrazole sulfonamide;SCHEMBL8477927;DTXSID40538357;MFCD08459239;AKOS013531016;AC-6116;AS-10993;1-Methyl-4-ethoxycarborylpyrazole-5-sulfonamide;4-ethoxycarbonyl-1-methylpyrazole-5-sulfonamide;Ethyl 1-methyl-5sulfamoylpyrazole-4-carboxylate;EN300-1618205;A842571

Suppliers and Price of Ethyl 1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Ethyl 1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylate 95+%
5g
$ 336.00

Matrix Scientific
Ethyl 1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylate 95+%
1g
$ 124.00

Matrix Scientific
Ethyl 1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylate 95+%
10g
$ 504.00

Crysdot
4-Ethyl-1H-pyrazole-5-sulfonamideacetate 97%
5g
$ 371.00

AK Scientific
Ethyl1-methyl-5-sulfamoylpyrazole-4-carboxylate
250mg
$ 95.00

AK Scientific
Ethyl1-methyl-5-sulfamoylpyrazole-4-carboxylate
100mg
$ 36.00

Total 51 raw suppliers

Chemical Property of Ethyl 1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.614
Boiling Point:449.504 °C at 760 mmHg
PKA:9.52±0.60(Predicted)
Flash Point:225.652 °C
PSA：112.66000
Density:1.54 g/cm³
LogP:1.02530
XLogP3:-0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:233.04702701
Heavy Atom Count:15
Complexity:337

Purity/Quality:

698% ^*data from raw suppliers

Ethyl 1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(N(N=C1)C)S(=O)(=O)N

Technology Process of Ethyl 1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylate

There total 5 articles about Ethyl 1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.4%

: 88398-82-7
ethyl 5-(chlorosulfonyl)-1-methyl-1H-pyrazole-4-carboxylate

: 88398-81-6
ethyl 1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylate

Guidance literature:: With ammonia; In water; at 50 ℃; for 2h;

Reference yield:

: 85290-80-8
ethyl 1-methylpyrazole-4-carboxylate

: 88398-81-6
ethyl 1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

2: 28percent aq. NH₄OH / tetrahydrofuran / 1 h / Ambient temperature

With ammonium hydroxide; In tetrahydrofuran;
DOI:10.1002/jhet.5570280808

Reference yield:

: 88398-78-1
1-methyl-5-hydroxypyrazol-4-carboxylic acid ethyl ester

: 88398-81-6
ethyl 1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydroxide / dimethyl sulfoxide / 0.5 h / 15 - 25 °C

1.2: 4 h / 0 - 5 °C

2.1: dodecane / Reflux

3.1: chlorine / dichloromethane; water / 0.5 h / 15 - 25 °C

4.1: ammonia / water / 2 h / 50 °C

With ammonia; chlorine; sodium hydroxide; In dodecane; dichloromethane; water; dimethyl sulfoxide;