5,5-diphenylpent-4-en-3-one

Base Information

• Chemical Name: 5,5-diphenylpent-4-en-3-one
• CAS No.: 104581-57-9
• Molecular Formula: C₁₇H₁₆O
• Molecular Weight: 236.313
• Mol file: 104581-57-9.mol

Synonyms:5,5-diphenylpent-4-en-3-one

Chemical Property of 5,5-diphenylpent-4-en-3-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,5-diphenylpent-4-en-3-one

There total 12 articles about 5,5-diphenylpent-4-en-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

iodobenzene (591-50-4) + 1-phenyl-pent-1-en-3-one (3152-68-9) → 5,5-diphenylpent-4-en-3-one (104581-57-9)

Guidance literature:

With tetrabutyl-ammonium chloride; sodium hydrogencarbonate; palladium diacetate; In N,N-dimethyl-formamide; at 60 ℃; for 8h;

DOI:10.1016/0040-4020(89)80112-7

Reference yield: 60.0%

2-methylene-1,1-diphenylbutan-1-ol (1116366-17-6) → 5,5-diphenylpent-4-en-3-one (104581-57-9)

Guidance literature:

With oxygen; cesium acetate; palladium dichloride; In N,N-dimethyl acetamide; acetonitrile; at 20 - 80 ℃; for 16.1667h; Large scale reaction;

DOI:10.1021/ol201177t

Reference yield: 59.0%

iodobenzene (591-50-4) + 1-phenyl-pent-1-en-3-one (3152-68-9) → 1,1-diphenylpentan-3-one (87351-01-7) + 5,5-diphenylpent-4-en-3-one (104581-57-9)

Guidance literature:

With formic acid; triethylamine; bis(triphenylphosphine) palladium (Il) acetate; In acetonitrile; at 80 ℃; for 6h; Yields of byproduct given;

DOI:10.1021/jo00171a016

upstream raw materials:

iodobenzene

4-penten-3-one

1-phenyl-pent-1-en-3-one

1-phenyl-1-pentyn-3-ol

Refernces

• 1、 Cacchi, Sandro,Fabrizi, Giancarlo,Gasparrini, Francesco,Pace, Paola,Villani, Claudio. "The utilization of supercritical carbon dioxide in the palladium- catalyzed hydroarylation of β-substituted-α,β-enones". . p. 650 - 652. Retrieved 2007/10/03.
• 2、 Amorese, A.,Arcadi, A.,Bernocchi, E.,Cacchi, S.,Cerrini, S.,et al.. "CONJUGATE ADDITION VS. VINYLIC SUBSTITUTION IN PALLADIUM-CATALYSED REACTION OF ARYL HALIDES WITH β-SUBSTITUTED-α,β-ENONES AND -ENALS". . p. 813 - 828. Retrieved 2007/10/02.