7-Quinolinemethanol

Base Information

• Chemical Name: 7-Quinolinemethanol
• CAS No.: 39982-49-5
• Molecular Formula: C10H9NO
• Molecular Weight: 159.188
• European Community (EC) Number: 845-378-5
• NSC Number: 136486
• UNII: LN43ZM8Z3A
• DSSTox Substance ID: DTXSID90193016
• Nikkaji Number: J501.110H
• Wikidata: Q83065733
• Mol file: 39982-49-5.mol

Synonyms:quinolin-7-ylmethanol;7-Quinolinemethanol;39982-49-5;7-quinolinylmethanol;(QUINOLIN-7-YL)METHANOL;LN43ZM8Z3A;NSC-136486;quinolin-7-yl methanol;UNII-LN43ZM8Z3A;SCHEMBL2865593;DTXSID90193016;RDBBFCMDRBOXIG-UHFFFAOYSA-N;MFCD03789622;NSC136486;AKOS006279783;AT24124;NSC 136486;SB68432;CS-0246020;FT-0741820;EN300-315307;A825795;J-524183;Z1198163277

Chemical Property of 7-Quinolinemethanol

Chemical Property:

• Vapor Pressure: 4.92E-05mmHg at 25°C
• Refractive Index: 1.667
• Boiling Point: 334.8 °C at 760 mmHg
• Flash Point: 156.3 °C
• PSA: 33.12000
• Density: 1.218 g/cm³
• LogP: 1.72710
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 159.068413911
• Heavy Atom Count: 12
• Complexity: 149

Purity/Quality:

99% ^*data from raw suppliers

(Quinolin-7-yl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C=C(C=C2)CO)N=C1

Technology Process of 7-Quinolinemethanol

There total 1 articles about 7-Quinolinemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Methyl-benzoic acid quinolin-7-ylmethyl ester (77934-76-0) → ortho-methylbenzoic acid (118-90-1) + (quinolin-7-yl)methanol (39982-49-5)

Guidance literature:

With water in alkaline medium; In acetone; Rate constant; Ambient temperature;

DOI:10.1016/S0040-4039(00)71154-3

Reference yield: 98.0%

(quinolin-7-yl)methanol (39982-49-5) → 7-bromomethyl-quinoline hydrobromide (188874-61-5)

Guidance literature:

With hydrogen bromide; acetic acid; at 70 ℃;

DOI:10.1016/S0960-894X(99)00196-1

Reference yield: 43.0%

(quinolin-7-yl)methanol (39982-49-5) → quinoline-7-carbaldehyde (49573-30-0)

Guidance literature:

With manganese(IV) oxide; In acetonitrile; at 80 ℃; for 12h;

upstream raw materials:

2-Methyl-benzoic acid quinolin-7-ylmethyl ester

Downstream raw materials:

7-bromomethyl-quinoline hydrobromide

(quinolin-7-yl)methylamine

(3R,4R)-4-[4-[3-(2-methoxy-benzyloxy)-propoxy]-phenyl]-3-(quinolin-7-yl-methoxy)-piperidine-1-carboxylic acid tert-butyl ester

(3R,4R)-4-[4-[3-(2-methoxy-benzyloxy)-propoxy]-phenyl]-3-(1,2,3,4-tetrahydro-quinolin-7-ylmethoxy)-piperidine-1-carboxylic acid tert-butyl ester

Refernces