((S)-1-((S)-2-((S)-2-(5-(2-aminomethyl-4-fluorophenyl)pyridin-3-yl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethylcarbamoyl)ethyl)methylcarbamic acid tert-butyl ester

Base Information

Chemical Name:((S)-1-((S)-2-((S)-2-(5-(2-aminomethyl-4-fluorophenyl)pyridin-3-yl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethylcarbamoyl)ethyl)methylcarbamic acid tert-butyl ester
CAS No.:1381963-39-8
Molecular Formula:C₃₃H₄₆FN₅O₄
Molecular Weight:595.758
Hs Code.:

((S)-1-((S)-2-((S)-2-(5-(2-aminomethyl-4-fluorophenyl)pyridin-3-yl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethylcarbamoyl)ethyl)methylcarbamic acid tert-butyl ester

Synonyms:((S)-1-((S)-2-((S)-2-(5-(2-aminomethyl-4-fluorophenyl)pyridin-3-yl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethylcarbamoyl)ethyl)methylcarbamic acid tert-butyl ester

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Chemical Property of ((S)-1-((S)-2-((S)-2-(5-(2-aminomethyl-4-fluorophenyl)pyridin-3-yl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethylcarbamoyl)ethyl)methylcarbamic acid tert-butyl ester

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Technology Process of ((S)-1-((S)-2-((S)-2-(5-(2-aminomethyl-4-fluorophenyl)pyridin-3-yl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethylcarbamoyl)ethyl)methylcarbamic acid tert-butyl ester

There total 1 articles about ((S)-1-((S)-2-((S)-2-(5-(2-aminomethyl-4-fluorophenyl)pyridin-3-yl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethylcarbamoyl)ethyl)methylcarbamic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1020176-96-8
((S)-1-{(S)-2-[(S)-2-(5-Bromo-pyridin-3-yl)-pyrrolidin-1-yl]-1-cyclohexyl-2-oxo-ethylcarbamoyl}-ethyl)-methyl-carbamic acid tert-butyl ester

: 850689-31-5
2-aminomethyl-4-fluorophenylboronic acid

: 1381963-40-1
C₂₆H₄₀N₄O₄

: 1381963-39-8
((S)-1-((S)-2-((S)-2-(5-(2-aminomethyl-4-fluorophenyl)pyridin-3-yl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethylcarbamoyl)ethyl)methylcarbamic acid tert-butyl ester

Guidance literature:: With sodium carbonate; bis-triphenylphosphine-palladium(II) chloride; In ethanol; toluene; at 80 ℃; for 12h; Inert atmosphere;

Reference yield:

: 1381963-39-8
((S)-1-((S)-2-((S)-2-(5-(2-aminomethyl-4-fluorophenyl)pyridin-3-yl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethylcarbamoyl)ethyl)methylcarbamic acid tert-butyl ester

: 787-70-2
4,4'-diphenic acid

: 1381963-22-9
N₄,N₄'-bis(2-(5-((S)-1-((S)-2-cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)pyrrolidin-2-yl)pyridin-3-yl)-5-fluorobenzyl)biphenyl-4,4'-dicarboxamide

Guidance literature:: ((S)-1-((S)-2-((S)-2-(5-(2-aminomethyl-4-fluorophenyl)pyridin-3-yl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethylcarbamoyl)ethyl)methylcarbamic acid tert-butyl ester; 4,4'-diphenic acid; With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 20.25h;

With sodium carbonate; In water; ethyl acetate; N,N-dimethyl-formamide;