Methyl α-azido-7α,12α-bis[p-(trifluoromethyl)phenylaminocarbonyloxy]-5β-cholan-24-oate

Base Information

Chemical Name:Methyl α-azido-7α,12α-bis[p-(trifluoromethyl)phenylaminocarbonyloxy]-5β-cholan-24-oate
CAS No.:467428-89-3
Molecular Formula:C₄₁H₄₉F₆N₅O₆
Molecular Weight:821.86
Hs Code.:

Synonyms:Methyl α-azido-7α,12α-bis[p-(trifluoromethyl)phenylaminocarbonyloxy]-5β-cholan-24-oate

Suppliers and Price of Methyl α-azido-7α,12α-bis[p-(trifluoromethyl)phenylaminocarbonyloxy]-5β-cholan-24-oate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methyl α-azido-7α,12α-bis[p-(trifluoromethyl)phenylaminocarbonyloxy]-5β-cholan-24-oate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Methyl α-azido-7α,12α-bis[p-(trifluoromethyl)phenylaminocarbonyloxy]-5β-cholan-24-oate

There total 3 articles about Methyl α-azido-7α,12α-bis[p-(trifluoromethyl)phenylaminocarbonyloxy]-5β-cholan-24-oate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 175340-05-3
Methyl 3α-azido-7α,12α-dihydroxy-5β-cholan-24-oate

: 1548-13-6
p-trifluoromethyl-phenylisocyanate

: 467428-89-3
Methyl α-azido-7α,12α-bis[p-(trifluoromethyl)phenylaminocarbonyloxy]-5β-cholan-24-oate

Guidance literature:: With chloro-trimethyl-silane; In dichloromethane; at 20 ℃; for 144h;
DOI:10.1039/b009215k

Reference yield:

: 1448-36-8
methyl cholate

: 467428-89-3
Methyl α-azido-7α,12α-bis[p-(trifluoromethyl)phenylaminocarbonyloxy]-5β-cholan-24-oate

Guidance literature:: Multi-step reaction with 3 steps

1: DEAD; DMAP; Ph₃P / tetrahydrofuran / 48 h / 20 °C

2: 4.57 g / NaN₃ / various solvent(s) / 48 h / 20 °C

3: 82 percent / Me₃SiCl / CH₂Cl₂ / 144 h / 20 °C

With dmap; chloro-trimethyl-silane; sodium azide; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; dichloromethane; 1: Mitsunobu reaction;
DOI:10.1039/b009215k

Reference yield:

: 175340-06-4
methyl 3β-mesyloxycholate

: 467428-89-3
Methyl α-azido-7α,12α-bis[p-(trifluoromethyl)phenylaminocarbonyloxy]-5β-cholan-24-oate

Guidance literature:: Multi-step reaction with 2 steps

1: 4.57 g / NaN₃ / various solvent(s) / 48 h / 20 °C

2: 82 percent / Me₃SiCl / CH₂Cl₂ / 144 h / 20 °C

With chloro-trimethyl-silane; sodium azide; In dichloromethane;
DOI:10.1039/b009215k