2-(4,5-dimethoxy-2-nitro-phenyl)-3-(4-dimethylamino-phenyl)-acrylonitrile

Base Information

• Chemical Name: 2-(4,5-dimethoxy-2-nitro-phenyl)-3-(4-dimethylamino-phenyl)-acrylonitrile
• CAS No.: 19017-80-2
• Molecular Formula: C₁₉H₁₉N₃O₄
• Molecular Weight: 353.378

Synonyms:2-(4,5-dimethoxy-2-nitro-phenyl)-3-(4-dimethylamino-phenyl)-acrylonitrile

Chemical Property of 2-(4,5-dimethoxy-2-nitro-phenyl)-3-(4-dimethylamino-phenyl)-acrylonitrile

Chemical Property:

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Technology Process of 2-(4,5-dimethoxy-2-nitro-phenyl)-3-(4-dimethylamino-phenyl)-acrylonitrile

There total 2 articles about 2-(4,5-dimethoxy-2-nitro-phenyl)-3-(4-dimethylamino-phenyl)-acrylonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(4,5-dimethoxy-2-nitrophenyl)acetonitrile (17354-04-0) + 4-dimethylamino-benzaldehyde (100-10-7) → 2-(4,5-dimethoxy-2-nitro-phenyl)-3-(4-dimethylamino-phenyl)-acrylonitrile (19017-80-2)

Guidance literature:

With piperidine; methanol;

DOI:10.1021/ja01596a039

Reference yield:

→ 2-(4,5-dimethoxy-2-nitro-phenyl)-3-(4-dimethylamino-phenyl)-acrylonitrile (19017-80-2)

Guidance literature:

entspr.Diether(II), 4-Dimethylaminobenzaldehyd, Piperidin;

Reference yield:

2-(4,5-dimethoxy-2-nitro-phenyl)-3-(4-dimethylamino-phenyl)-acrylonitrile (19017-80-2) → 4-(5,6-dimethoxy-indol-3-ylmethyl)-N,N-dimethyl-aniline (110049-58-6)

Guidance literature:

With palladium on activated charcoal; ethyl acetate; at 80 ℃; Hydrogenation;

DOI:10.1021/ja01596a039

upstream raw materials:

2-(4,5-dimethoxy-2-nitrophenyl)acetonitrile

4-dimethylamino-benzaldehyde

Downstream raw materials:

4-(5,6-dimethoxy-indol-3-ylmethyl)-N,N-dimethyl-aniline

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