N-(4-Cyano-3-phenylthiophenyl)-3,3,3,-trifluoro-2-hydroxy-2-methyl propanamide

Base Information

Chemical Name:N-(4-Cyano-3-phenylthiophenyl)-3,3,3,-trifluoro-2-hydroxy-2-methyl propanamide
CAS No.:148301-97-7
Molecular Formula:C₁₇H₁₃F₃N₂O₂S
Molecular Weight:366.364
Hs Code.:

Synonyms:N-(4-Cyano-3-phenylthiophenyl)-3,3,3,-trifluoro-2-hydroxy-2-methyl propanamide

Suppliers and Price of N-(4-Cyano-3-phenylthiophenyl)-3,3,3,-trifluoro-2-hydroxy-2-methyl propanamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(4-Cyano-3-phenylthiophenyl)-3,3,3,-trifluoro-2-hydroxy-2-methyl propanamide

Chemical Property:

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Technology Process of N-(4-Cyano-3-phenylthiophenyl)-3,3,3,-trifluoro-2-hydroxy-2-methyl propanamide

There total 3 articles about N-(4-Cyano-3-phenylthiophenyl)-3,3,3,-trifluoro-2-hydroxy-2-methyl propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 20925-27-3
4-amino-2-chlorobenzonitrile

: 148301-97-7
N-(4-Cyano-3-phenylthiophenyl)-3,3,3,-trifluoro-2-hydroxy-2-methyl propanamide

Guidance literature:: Multi-step reaction with 2 steps

1: 30 percent / dimethylformamide / 16 h / 140 °C

2: dimethylformamide / Ambient temperature

In N,N-dimethyl-formamide;
DOI:10.1021/jm960365n

Reference yield:

: 3111-52-2
potassium thiophenolate

: 148301-97-7
N-(4-Cyano-3-phenylthiophenyl)-3,3,3,-trifluoro-2-hydroxy-2-methyl propanamide

Guidance literature:: Multi-step reaction with 2 steps

1: 30 percent / dimethylformamide / 16 h / 140 °C

2: dimethylformamide / Ambient temperature

In N,N-dimethyl-formamide;
DOI:10.1021/jm960365n