6-N-benzoyl-9-(3,5-O-bis-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)adenine

Base Information

Chemical Name:6-N-benzoyl-9-(3,5-O-bis-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)adenine
CAS No.:82434-61-5
Molecular Formula:C₅₉H₅₃N₅O₉
Molecular Weight:976.098
Hs Code.:

Synonyms:6-N-benzoyl-9-(3,5-O-bis-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)adenine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-N-benzoyl-9-(3,5-O-bis-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)adenine

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Technology Process of 6-N-benzoyl-9-(3,5-O-bis-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)adenine

There total 3 articles about 6-N-benzoyl-9-(3,5-O-bis-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)adenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 4546-55-8
N-benzoyladenosine

: 82434-61-5
6-N-benzoyl-9-(3,5-O-bis-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)adenine

: 96026-73-2
6-N-benzoyl-9-(2,5-O-bis-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)adenine

Guidance literature:: With pyridine; triethylamine; at 20 ℃;
DOI:10.1021/jm050401v

Reference yield: 10.0%

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 4546-55-8
N-benzoyladenosine

: 129666-75-7,81246-82-4
6-N-benzoyl-5'-O-(4,4'-dimethoxytrityl)adenosine

: 82434-61-5
6-N-benzoyl-9-(3,5-O-bis-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)adenine

: 96026-73-2
6-N-benzoyl-9-(2,5-O-bis-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)adenine

Guidance literature:: With pyridine; silver nitrate; In tetrahydrofuran; for 1h; Ambient temperature;
DOI:10.1139/v82-165

Reference yield:

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 4546-55-8
N-benzoyladenosine

: 82434-61-5
6-N-benzoyl-9-(3,5-O-bis-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl)adenine

Guidance literature:: N-benzoyladenosine; With pyridine; at 20 ℃;

4,4'-dimethoxytrityl chloride; With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 20 ℃;
DOI:10.1081/NCN-120022734