Chemical Property of 13,14-Didehydromatridin-15-one
Chemical Property:
- Vapor Pressure:1.92E-07mmHg at 25°C
- Refractive Index:1.603
- Boiling Point:425.4oC at 760 mmHg
- Flash Point:194oC
- PSA：23.55000
- Density:1.19g/cm3
- LogP:1.52350
- Storage Temp.:-20°C Freezer
- Solubility.:Acetone; Dichloromethane
- Purity/Quality:
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≥98% *data from raw suppliers
Sophocarpine *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
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Description
A tetracyclic alkaloid present in Sophora species, this base crystallizes from H20
as the monohydrate, m.p. 54-5°C which becomes anhydrous in vacuo. It has
[α]18D - 29.44° (EtOH) and yields the following salts: hydrochloride, m.p. >
300°C; hydriodide, m.p. 277-9°C; aurichloride, m.p. l66-7°C; platinichloride,
m.p. 207-212°C (dec.); picrate, m.p. ISS-7°C and the methiodide, m.p. 200-2°C. Reduction of the base by electrolysis yields a crystalline, volatile base,
ClsH26N2, b.p. l53-4°C/5 mm; [α]D - 26.2° (EtOH) and giving a methiodide
with a melting point above 300°C. Attempted degradation by the Hofmann
process has proved unsuccessful.
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Uses
Sophocarpine Monohydrate alleviates non-alcoholic steatohepatitis, which is a resultant effect of non-alcoholic fatty lifer disease. Admission of 13,14-Didehydromatridin-15-one results in a decrease in liver weight and serum lipids. Antiviral agent, Sophocarpine also displays a profound effect against coxsackievirus and therapeutical effects of viral myocarditis.
