TAEM

Base Information

Chemical Name:TAEM
CAS No.:158183-05-2
Molecular Formula:C₂₀H₂₂N₄O₄S₃
Molecular Weight:478.617
Hs Code.:
Mol file:158183-05-2.mol

Synonyms:2-MERCAPTOBENZOYL-ALPHA-(2-AMINOTHIAZOL-4-YL)-ALPHA-[(TERT-BUTOXYCARBONYL)ISOPROPOXYIMINO]ACETATE;2-Mercaptobenzothiazolyl (Z)-2-(2-aminothiazol-4-yl)-2-(2-t-butoxycarbonylprop-2-oxyimino) acetate;2-MERCAPTOBENZOTHIAZOLYL-(Z)(2-AMINOTHIAZOLE-4YL)-2-(TERT-BUTOXYCARBONYL)ISOPROPOXYIMINO ACETATE;2-(2-AMINO-4-THIAZOLE)-2-(TERTBUTOXY ISOPROPOXYIMINO)ACETATE THIOBENZOTHIAZOLE ESTER;BENZOTHIAZOL-ALPHA-YL-(Z)-2-(TERT-BUTOXYCARBONYLPROP)-2-OXYIMINO-2-(2-AMINOTHIAZOLE-4-YL) THIOACETATE;(Z)-TERT-BUTYL 2-(1-(2-AMINOTHIAZOL-4-YL)-2-(BENZO[D]THIAZOL-2-YLTHIO)-2-OXOETHYLIDENEAMINOOXY)-2-METHYLPROPANOATE;propanoic acid (z)-2-[[[1-(2-amino-4-thiazolyl)-2-(2-benzothiazolylthio)-2-oxoethylidene]amino]oxy]-2-methyl-1,1-dimethylethyl ester;S-2-BENZOTHIAZOYL-(Z)-2-(1-TERT-BUTOXYCANBONYL-1-METHYLETHOXYIMINO)-(2-AMINO-THIAZOL-4-YL) ACETATE

Suppliers and Price of TAEM

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2-Mercaptobenzothiazolyl
50mg
$ 489.00

Usbiological
2-Mercaptobenzothiazolyl-
500mg
$ 410.00

AHH
2-Mercaptobenzoyl-alpha-(2-aminothiazol-4-yl)-alpha-[(tertbutoxycarbonyl)]isopropoxyimino]acetate 98%
100g
$ 658.00

Total 77 raw suppliers

Chemical Property of TAEM

Chemical Property:

Vapor Pressure:2.26E-15mmHg at 25°C
Melting Point:138-140℃
Refractive Index:1.671
Boiling Point:621.6°C at 760 mmHg
PKA:1.89±0.10(Predicted)
Flash Point:329.7°C
PSA：198.54000
Density:1.41g/cm³
LogP:5.07610

Purity/Quality:

99% ^*data from raw suppliers

2-Mercaptobenzothiazolyl ^*data from reagent suppliers

Safty Information:

Pictogram(s): R53:;
Hazard Codes:R53:;
Statements: R53:;
Safety Statements: S61:;

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of TAEM

There total 3 articles about TAEM which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.5%

: 120-78-5
di(benzothiazol-2-yl)disulfide

: 86299-47-0
(Z)-2-(2-aminothiazol-4-yl)-2-(1-tert-butoxycarbonyl-1-methylethoxy)iminoacetic acid

: 89604-92-2,158183-05-2
2-benzothiazolyl 2-(2-aminothiazol-4-yl)-2-<<1-(tert-butoxycarbonyl)-1-methylethoxy>imino>thioacetate

Guidance literature:: With pyridine; N,N-dimethyl-aniline; triethyl phosphite; In acetonitrile; benzene; at 18 - 25 ℃; for 0.5h; Reagent/catalyst; Microwave irradiation; Green chemistry;

Reference yield: 92.6%

: 120-78-5
di(benzothiazol-2-yl)disulfide

: 86299-47-0
(Z)-2-(2-aminothiazol-4-yl)-2-(1-tert-butoxycarbonyl-1-methylethoxy)iminoacetic acid

: 89604-92-2,158183-05-2
(Z)-2-<<<1-(2-amino-4-thiazolyl)-2-<(2-benzothiazolyl)thio>-2-oxoethylidene>amino>oxy>-2-methyl propanoic acid 1,1-dimethylethyl ester

Guidance literature:: di(benzothiazol-2-yl)disulfide; (Z)-2-(2-aminothiazol-4-yl)-2-(1-tert-butoxycarbonyl-1-methylethoxy)iminoacetic acid; With pyridine; triethylamine; In acetonitrile; at 21 - 30 ℃; for 0.833333h;

With triethyl phosphite; In acetonitrile; at 21 ℃; for 5.5h; Temperature;

Reference yield: 92.4%

: 120-78-5
di(benzothiazol-2-yl)disulfide

: 86299-47-0
(Z)-2-(2-aminothiazol-4-yl)-2-(1-tert-butoxycarbonyl-1-methylethoxy)iminoacetic acid

: 89604-92-2,158183-05-2
(Z)-2-<<<1-(2-amino-4-thiazolyl)-2-<(2-benzothiazolyl)thio>-2-oxoethylidene>amino>oxy>-2-methyl propanoic acid 1,1-dimethylethyl ester

: 149-30-4,118090-09-8
2-Mercaptobenzothiazole

Guidance literature:: di(benzothiazol-2-yl)disulfide; (Z)-2-(2-aminothiazol-4-yl)-2-(1-tert-butoxycarbonyl-1-methylethoxy)iminoacetic acid; With pyridine; In acetonitrile; at 25 ℃; for 0.5h; Inert atmosphere;

With phosphorous acid trimethyl ester; In acetonitrile; at 25 ℃; for 7h; Inert atmosphere;
DOI:10.1007/s11164-012-0583-0