3-benzyloxy-6-bromo-4-methoxy-pyridine-2-carboxylic acid 4-fluorobenzylamide

Base Information

Chemical Name:3-benzyloxy-6-bromo-4-methoxy-pyridine-2-carboxylic acid 4-fluorobenzylamide
CAS No.:851441-90-2
Molecular Formula:C₂₁H₁₈BrFN₂O₃
Molecular Weight:445.288
Hs Code.:

Synonyms:3-benzyloxy-6-bromo-4-methoxy-pyridine-2-carboxylic acid 4-fluorobenzylamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-benzyloxy-6-bromo-4-methoxy-pyridine-2-carboxylic acid 4-fluorobenzylamide

Chemical Property:

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Technology Process of 3-benzyloxy-6-bromo-4-methoxy-pyridine-2-carboxylic acid 4-fluorobenzylamide

There total 1 articles about 3-benzyloxy-6-bromo-4-methoxy-pyridine-2-carboxylic acid 4-fluorobenzylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 321596-54-7
6-BROMO-3-BENZYLOXY-4-METHOXYPYRIDINE-2-CARBOXYLIC ACID

: 140-75-0
para-fluorobenzylamine

: 851441-90-2
3-benzyloxy-6-bromo-4-methoxy-pyridine-2-carboxylic acid 4-fluorobenzylamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; HATU; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 12h;

Reference yield:

: 851441-90-2
3-benzyloxy-6-bromo-4-methoxy-pyridine-2-carboxylic acid 4-fluorobenzylamide

: 3-hydroxy-4-methoxy-pyridine-2-carboxylic acid 4-fluorobenzyl-amide

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; ethyl acetate; at 20 ℃; for 1h;

Reference yield:

: 110-89-4
piperidine

: 851441-90-2
3-benzyloxy-6-bromo-4-methoxy-pyridine-2-carboxylic acid 4-fluorobenzylamide

: 5'-benzyloxy-4'-methoxy-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-6'-carboxylic acid 4-fluoro-benzylamide

Guidance literature:: With caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; palladium diacetate; In 1,4-dioxane; at 110 ℃; for 18h;