methyl (2S)-2-[({1-[(2R,3R,4R,5R)-3,4-bis(benzyloxy)-5-[(benzyloxy)methyl]-1-(trifluoroacetyl)pyrrolidin-2-yl]cyclopropyl}carbonyl)amino]-3-phenylpropanoate

Base Information

Chemical Name:methyl (2S)-2-[({1-[(2R,3R,4R,5R)-3,4-bis(benzyloxy)-5-[(benzyloxy)methyl]-1-(trifluoroacetyl)pyrrolidin-2-yl]cyclopropyl}carbonyl)amino]-3-phenylpropanoate
CAS No.:1158917-77-1
Molecular Formula:C₄₂H₄₃F₃N₂O₇
Molecular Weight:744.808
Hs Code.:

methyl (2S)-2-[({1-[(2R,3R,4R,5R)-3,4-bis(benzyloxy)-5-[(benzyloxy)methyl]-1-(trifluoroacetyl)pyrrolidin-2-yl]cyclopropyl}carbonyl)amino]-3-phenylpropanoate

Synonyms:methyl (2S)-2-[({1-[(2R,3R,4R,5R)-3,4-bis(benzyloxy)-5-[(benzyloxy)methyl]-1-(trifluoroacetyl)pyrrolidin-2-yl]cyclopropyl}carbonyl)amino]-3-phenylpropanoate

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Chemical Property of methyl (2S)-2-[({1-[(2R,3R,4R,5R)-3,4-bis(benzyloxy)-5-[(benzyloxy)methyl]-1-(trifluoroacetyl)pyrrolidin-2-yl]cyclopropyl}carbonyl)amino]-3-phenylpropanoate

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Technology Process of methyl (2S)-2-[({1-[(2R,3R,4R,5R)-3,4-bis(benzyloxy)-5-[(benzyloxy)methyl]-1-(trifluoroacetyl)pyrrolidin-2-yl]cyclopropyl}carbonyl)amino]-3-phenylpropanoate

There total 1 articles about methyl (2S)-2-[({1-[(2R,3R,4R,5R)-3,4-bis(benzyloxy)-5-[(benzyloxy)methyl]-1-(trifluoroacetyl)pyrrolidin-2-yl]cyclopropyl}carbonyl)amino]-3-phenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 1158917-72-6
1-[(2R,3R,4R,5R)-3,4-bis(benzyloxy)-5-[(benzyloxy)methyl]-1-(trifluoroacetyl)pyrrolidin-2-yl]cyclopropanecarboxylic acid

: 7524-50-7
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

: 1158917-77-1
methyl (2S)-2-[({1-[(2R,3R,4R,5R)-3,4-bis(benzyloxy)-5-[(benzyloxy)methyl]-1-(trifluoroacetyl)pyrrolidin-2-yl]cyclopropyl}carbonyl)amino]-3-phenylpropanoate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; In dichloromethane; at 20 ℃; Cooling with ice; Inert atmosphere;
DOI:10.1021/jo9004684