2-(2-naphthyl)-5-(4-nitrophenyl)-4-acetyl-2,3-dihydro-1,3,4-oxadiazoline

Base Information

Chemical Name:2-(2-naphthyl)-5-(4-nitrophenyl)-4-acetyl-2,3-dihydro-1,3,4-oxadiazoline
CAS No.:1357078-14-8
Molecular Formula:C₂₀H₁₅N₃O₄
Molecular Weight:361.357
Hs Code.:

Synonyms:2-(2-naphthyl)-5-(4-nitrophenyl)-4-acetyl-2,3-dihydro-1,3,4-oxadiazoline

Suppliers and Price of 2-(2-naphthyl)-5-(4-nitrophenyl)-4-acetyl-2,3-dihydro-1,3,4-oxadiazoline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(2-naphthyl)-5-(4-nitrophenyl)-4-acetyl-2,3-dihydro-1,3,4-oxadiazoline

Chemical Property:

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Technology Process of 2-(2-naphthyl)-5-(4-nitrophenyl)-4-acetyl-2,3-dihydro-1,3,4-oxadiazoline

There total 4 articles about 2-(2-naphthyl)-5-(4-nitrophenyl)-4-acetyl-2,3-dihydro-1,3,4-oxadiazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 344938-46-1
LASSBio-1524

: 108-24-7
acetic anhydride

: 1357078-14-8
2-(2-naphthyl)-5-(4-nitrophenyl)-4-acetyl-2,3-dihydro-1,3,4-oxadiazoline

Guidance literature:: for 1h; Reflux;
DOI:10.1016/j.bmc.2011.11.057

Reference yield:

: 3007-91-8
ethyl-2-naphthoate

: 1357078-14-8
2-(2-naphthyl)-5-(4-nitrophenyl)-4-acetyl-2,3-dihydro-1,3,4-oxadiazoline

Guidance literature:: Multi-step reaction with 3 steps

1: hydrazine hydrate / ethanol / Reflux

2: acetic acid / ethanol; water / 5 h / Reflux

3: 1 h / Reflux

With hydrazine hydrate; acetic acid; In ethanol; water;
DOI:10.1016/j.bmc.2011.11.057

Reference yield:

: 93-09-4
naphthalene-2-carboxylate

: 1357078-14-8
2-(2-naphthyl)-5-(4-nitrophenyl)-4-acetyl-2,3-dihydro-1,3,4-oxadiazoline

Guidance literature:: Multi-step reaction with 4 steps

1: sulfuric acid / Reflux

2: hydrazine hydrate / ethanol / Reflux

3: acetic acid / ethanol; water / 5 h / Reflux

4: 1 h / Reflux

With sulfuric acid; hydrazine hydrate; acetic acid; In ethanol; water;
DOI:10.1016/j.bmc.2011.11.057