(2'S,3'S) ethyl 2-O-chloroacetyl-3-O,4-O-[2',3'-dimethoxybutan-2',3'-diyl]-1-thio-α-D-mannopyranoside

Base Information

Chemical Name:(2'S,3'S) ethyl 2-O-chloroacetyl-3-O,4-O-[2',3'-dimethoxybutan-2',3'-diyl]-1-thio-α-D-mannopyranoside
CAS No.:270087-61-1
Molecular Formula:C₂₄H₂₉ClO₆S
Molecular Weight:481.01
Hs Code.:

Synonyms:(2'S,3'S) ethyl 2-O-chloroacetyl-3-O,4-O-[2',3'-dimethoxybutan-2',3'-diyl]-1-thio-α-D-mannopyranoside

Suppliers and Price of (2'S,3'S) ethyl 2-O-chloroacetyl-3-O,4-O-[2',3'-dimethoxybutan-2',3'-diyl]-1-thio-α-D-mannopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2'S,3'S) ethyl 2-O-chloroacetyl-3-O,4-O-[2',3'-dimethoxybutan-2',3'-diyl]-1-thio-α-D-mannopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2'S,3'S) ethyl 2-O-chloroacetyl-3-O,4-O-[2',3'-dimethoxybutan-2',3'-diyl]-1-thio-α-D-mannopyranoside

There total 9 articles about (2'S,3'S) ethyl 2-O-chloroacetyl-3-O,4-O-[2',3'-dimethoxybutan-2',3'-diyl]-1-thio-α-D-mannopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: (2'S,3'S) ethyl 6-O-tert-butyldimethylsilyl-2-O-chloroacetyl-3-O,4-O-[2',3'-dimethoxybutan-2',3'-diyl]-1-thio-α-D-mannopyranoside

: 270087-61-1
(2'S,3'S) ethyl 2-O-chloroacetyl-3-O,4-O-[2',3'-dimethoxybutan-2',3'-diyl]-1-thio-α-D-mannopyranoside

Guidance literature:: With hydrogen fluoride; In acetonitrile; at 20 ℃; for 1h;
DOI:10.1016/S0957-4166(99)00519-4

Reference yield:

: 3254-16-8,4435-05-6,19189-54-9,29748-21-8,50801-29-1,64727-26-0,64727-27-1,65338-02-5,67672-68-8,78418-55-0,80877-03-8,103002-27-3,103002-29-5,132562-62-0
3,4,6-tri-O-acetyl-1,2-O-(1-methoxyethylidene)-β-D-mannopyranose

: 270087-61-1
(2'S,3'S) ethyl 2-O-chloroacetyl-3-O,4-O-[2',3'-dimethoxybutan-2',3'-diyl]-1-thio-α-D-mannopyranoside

Guidance literature:: Multi-step reaction with 7 steps

1: K₂CO₃ / methanol / 7 h / 20 °C

2: imidazole / tetrahydrofuran / 2 h / 20 °C

3: tetrabutylammonium iodide; NaH / dimethylformamide / 14 h / 20 °C

4: 72 percent / HgBr₂; 4A/5A MS / acetonitrile / 4.5 h / 60 °C

5: K₂CO₃ / methanol / 14 h / 20 °C

6: 0.88 g / pyridine / CH₂Cl₂ / 1.25 h / 0 °C

7: 87 percent / 48 percent aq. HF / acetonitrile / 1 h / 20 °C

With pyridine; 1H-imidazole; hydrogen fluoride; tetra-(n-butyl)ammonium iodide; sodium hydride; potassium carbonate; mercury dibromide; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile; 1: Deacetylation / 2: Etherification / 3: Benzylation / 4: Thioetherification / 5: Deacetylation / 6: Acetylation / 7: Desilylation;
DOI:10.1016/S0957-4166(99)00519-4

Reference yield:

: 29073-91-4,55865-04-8,138196-19-7
1,2-O-(1-methoxyethylidene)-β-D-mannopyranose

: 270087-61-1
(2'S,3'S) ethyl 2-O-chloroacetyl-3-O,4-O-[2',3'-dimethoxybutan-2',3'-diyl]-1-thio-α-D-mannopyranoside

Guidance literature:: Multi-step reaction with 6 steps

1: imidazole / tetrahydrofuran / 2 h / 20 °C

2: tetrabutylammonium iodide; NaH / dimethylformamide / 14 h / 20 °C

3: 72 percent / HgBr₂; 4A/5A MS / acetonitrile / 4.5 h / 60 °C

4: K₂CO₃ / methanol / 14 h / 20 °C

5: 0.88 g / pyridine / CH₂Cl₂ / 1.25 h / 0 °C

6: 87 percent / 48 percent aq. HF / acetonitrile / 1 h / 20 °C

With pyridine; 1H-imidazole; hydrogen fluoride; tetra-(n-butyl)ammonium iodide; sodium hydride; potassium carbonate; mercury dibromide; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile; 1: Etherification / 2: Benzylation / 3: Thioetherification / 4: Deacetylation / 5: Acetylation / 6: Desilylation;
DOI:10.1016/S0957-4166(99)00519-4