Allyl-((2R,3R,4R,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-phenylselanyl-tetrahydro-pyran-3-yl)-amine

Base Information

• Chemical Name: Allyl-((2R,3R,4R,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-phenylselanyl-tetrahydro-pyran-3-yl)-amine
• CAS No.: 186092-37-5
• Molecular Formula: C₃₆H₃₉NO₄Se
• Molecular Weight: 628.67
• Mol file: 186092-37-5.mol

Synonyms:Allyl-((2R,3R,4R,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-phenylselanyl-tetrahydro-pyran-3-yl)-amine

Chemical Property of Allyl-((2R,3R,4R,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-phenylselanyl-tetrahydro-pyran-3-yl)-amine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of Allyl-((2R,3R,4R,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-phenylselanyl-tetrahydro-pyran-3-yl)-amine

There total 1 articles about Allyl-((2R,3R,4R,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-phenylselanyl-tetrahydro-pyran-3-yl)-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Phenyl 2-azido-3,4,6-tri-O-benzyl-2-deoxy-1-seleno-α-D-galactopyranoside (153808-91-4) → Allyl-((2R,3R,4R,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-phenylselanyl-tetrahydro-pyran-3-yl)-amine (186092-37-5)

Guidance literature:

Multi-step reaction with 2 steps

1: HS(CH₂)3SH, NaBH₄, NEt₃ / propan-2-ol / 4 h / 45 °C

2: NaH / tetrahydrofuran / 3 h / Ambient temperature

With 1.3-propanedithiol; sodium tetrahydroborate; sodium hydride; triethylamine; In tetrahydrofuran; isopropyl alcohol;

DOI:10.1016/S0040-4039(96)02153-3

Reference yield: 72.0%

Allyl-((2R,3R,4R,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-phenylselanyl-tetrahydro-pyran-3-yl)-amine (186092-37-5) → (3R,3aR,5R,6R,7R,7aS)-6,7-Bis-benzyloxy-5-benzyloxymethyl-3-methyl-octahydro-pyrano[3,2-b]pyrrole

Guidance literature:

With triethyl borane; tri-n-butyl-tin hydride; In benzene; for 0.166667h; Ambient temperature;

DOI:10.1016/S0040-4039(96)02153-3

upstream raw materials:

Phenyl 2-azido-3,4,6-tri-O-benzyl-2-deoxy-1-seleno-α-D-galactopyranoside