3-decyloxybenzamide

Base Information

• Chemical Name: 3-decyloxybenzamide
• CAS No.: 1122677-75-1
• Molecular Formula: C₁₇H₂₇NO₂
• Molecular Weight: 277.407
• Mol file: 1122677-75-1.mol

Synonyms:3-decyloxybenzamide

Chemical Property of 3-decyloxybenzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-decyloxybenzamide

There total 6 articles about 3-decyloxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(decyloxy)benzoyl chloride (158136-18-6) → 3-decyloxybenzamide (1122677-75-1)

Guidance literature:

With ammonium hydroxide; In 1,4-dioxane; Cooling with ice;

DOI:10.3390/molecules25235761

Reference yield:

3-hydroxybenzamide (618-49-5) → 3-decyloxybenzamide (1122677-75-1)

Guidance literature:

With potassium carbonate; sodium iodide; In N,N-dimethyl-formamide; at 60 ℃;

DOI:10.1016/j.bmcl.2008.11.021

Reference yield:

3-(decyloxy)benzoic acid (79785-46-9) → 3-decyloxybenzamide (1122677-75-1)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride; N,N-dimethyl-formamide / toluene / 12 h / Reflux

2: ammonium hydroxide / 1,4-dioxane / Cooling with ice

With ammonium hydroxide; thionyl chloride; N,N-dimethyl-formamide; In 1,4-dioxane; toluene;

DOI:10.3390/molecules25235761

upstream raw materials:

3-hydroxybenzamide

methyl 3-decyloxybenzoate

3-(decyloxy)benzoic acid

1-bromo dodecane

Refernces

• 1、 Czaplewski, Lloyd G.,Collins, Ian,Boyd, E. Andrew,Brown, David,East, Stephen P.,Gardiner, Mihaly,Fletcher, Rowena,Haydon, David J.,Henstock, Vincent,Ingram, Peter,Jones, Clare,Noula, Caterina,Kennison, Leanne,Rockley, Chris,Rose, Valerie,Thomaides-Brears, Helena B.,Ure, Rebecca,Whittaker, Mark,Stokes, Neil R.. "Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ". scheme or table. p. 524 - 527. Retrieved 2011/02/28.