(2,2,2-trichloroacetyl)carbamic acid 1-(2-phenylethane)allyl ester

Base Information

• Chemical Name: (2,2,2-trichloroacetyl)carbamic acid 1-(2-phenylethane)allyl ester
• CAS No.: 1127647-32-8
• Molecular Formula: C₁₄H₁₄Cl₃NO₃
• Molecular Weight: 350.629
• Mol file: 1127647-32-8.mol

Synonyms:(2,2,2-trichloroacetyl)carbamic acid 1-(2-phenylethane)allyl ester

Chemical Property of (2,2,2-trichloroacetyl)carbamic acid 1-(2-phenylethane)allyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (2,2,2-trichloroacetyl)carbamic acid 1-(2-phenylethane)allyl ester

There total 1 articles about (2,2,2-trichloroacetyl)carbamic acid 1-(2-phenylethane)allyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-phenylpent-1-en-3-ol (37904-38-4) + Trichloroacetyl isocyanate (3019-71-4) → (2,2,2-trichloroacetyl)carbamic acid 1-(2-phenylethane)allyl ester (1127647-32-8)

Guidance literature:

In tetrahydrofuran; at 0 - 25 ℃;

DOI:10.1055/s-0028-1083282

Reference yield: 90.0%

(2,2,2-trichloroacetyl)carbamic acid 1-(2-phenylethane)allyl ester (1127647-32-8) → 2,2,2-trichloro-N-(5-phenylpent-2-enyl)acetamide

Guidance literature:

With lithium chloride; palladium dichloride; In tetrahydrofuran; at 100 ℃; for 0.333333h; Microwave irradiation;

DOI:10.1055/s-0028-1083282

Reference yield:

(2,2,2-trichloroacetyl)carbamic acid 1-(2-phenylethane)allyl ester (1127647-32-8) → (4RS,5SR)-4-(1-Chloromethyl)-5-(2-phenylethyl)-1,3-oxazolidin-2-one

Guidance literature:

(2,2,2-trichloroacetyl)carbamic acid 1-(2-phenylethane)allyl ester; With lithium chloride; copper dichloride; In tetrahydrofuran; at 25 ℃; for 0.0833333h;

With palladium diacetate; In tetrahydrofuran; at 25 ℃; for 12h; regioselective reaction;

DOI:10.1055/s-0028-1083282

upstream raw materials:

5-phenylpent-1-en-3-ol

Trichloroacetyl isocyanate