Z-3-thiosemicarbazone of 1-acetylisatin

Base Information

• Chemical Name: Z-3-thiosemicarbazone of 1-acetylisatin
• CAS No.: 110829-23-7
• Molecular Formula: C₁₁H₁₀N₄O₂S
• Molecular Weight: 262.292
• Mol file: 110829-23-7.mol

Synonyms:Z-3-thiosemicarbazone of 1-acetylisatin

Chemical Property of Z-3-thiosemicarbazone of 1-acetylisatin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Z-3-thiosemicarbazone of 1-acetylisatin

There total 1 articles about Z-3-thiosemicarbazone of 1-acetylisatin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

1-acetyl-1H-indole-2,3-dione (574-17-4) + thiosemicarbazide (79-19-6) → (Z)-2-(2-oxoindolin-3-ylidene)-hydrazinecarbothioamide (487-16-1,26134-45-2,27830-79-1,1165809-20-0) + Z-3-thiosemicarbazone of 1-acetylisatin (110829-23-7) + o-(acetylamino)phenylglyoxylothiosemicarbazide (110829-24-8)

Guidance literature:

In N,N-dimethyl acetamide; Product distribution; other solvent;

Reference yield:

Z-3-thiosemicarbazone of 1-acetylisatin (110829-23-7) → (Z)-2-(2-oxoindolin-3-ylidene)-hydrazinecarbothioamide (487-16-1,26134-45-2,27830-79-1,1165809-20-0)

Guidance literature:

1.) heated with alkali; 2.) acidified;

upstream raw materials:

1-acetyl-1H-indole-2,3-dione

thiosemicarbazide

Downstream raw materials:

(Z)-2-(2-oxoindolin-3-ylidene)-hydrazinecarbothioamide