5-Amino-2-bromo-3-picoline

Base Information

Chemical Name:5-Amino-2-bromo-3-picoline
CAS No.:38186-83-3
Molecular Formula:C6H7BrN2
Molecular Weight:187.04
Hs Code.:29333999
European Community (EC) Number:833-076-6
DSSTox Substance ID:DTXSID00494243
Wikidata:Q72438684
Mol file:38186-83-3.mol

Synonyms:5-Amino-2-bromo-3-picoline;38186-83-3;5-Amino-2-bromo-3-methylpyridine;6-bromo-5-methylpyridin-3-amine;3-Pyridinamine, 6-bromo-5-methyl-;MFCD03095085;EN300-131929;SCHEMBL2407304;DTXSID00494243;IEONGQZSAUAAKH-UHFFFAOYSA-N;2-bromo-5-amino-3-methylpyridine;AM953;BDBM626016;CS-D0970;6-Bromo-5-methyl-pyridin-3-ylamine;AKOS005257957;AB13464;DS-0481;SB40595;5-amino-2-bromo-3-picoline, AldrichCPR;AC-23438;SY024695;4-(Cyclopentylaminocarbonyl)phenylboronicacid;A6481;FT-0600608;J-518412;5-Amino-2-bromo-3-picoline (5-Amino-2-bromo-3-methylpyridine)

Suppliers and Price of 5-Amino-2-bromo-3-picoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Amino-2-bromo-3-picoline
250mg
$ 45.00

TCI Chemical
5-Amino-2-bromo-3-methylpyridine >95.0%(GC)(T)
1g
$ 23.00

TCI Chemical
5-Amino-2-bromo-3-methylpyridine >95.0%(GC)(T)
5g
$ 63.00

SynQuest Laboratories
5-Amino-2-bromo-3-methylpyridine
5 g
$ 128.00

Matrix Scientific
5-Amino-2-bromo-3-picoline 95+%
5g
$ 103.00

Matrix Scientific
5-Amino-2-bromo-3-picoline 95+%
25g
$ 307.00

Crysdot
5-Amino-2-bromo-3-picoline 95+%
100g
$ 312.00

Chemcia Scientific
6-Bromo-5-methyl-pyridin-3-ylamine 97%
250 G
$ 1100.00

Biosynth Carbosynth
5-Amino-2-bromo-3-methylpyridine
10 g
$ 282.50

Biosynth Carbosynth
5-Amino-2-bromo-3-methylpyridine
5 g
$ 176.60

Total 88 raw suppliers

Chemical Property of 5-Amino-2-bromo-3-picoline

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
Melting Point:97-100℃
Refractive Index:1.617
Boiling Point:304.978 °C at 760 mmHg
PKA:2.02±0.20(Predicted)
Flash Point:138.246 °C
PSA：38.91000
Density:1.593 g/cm³
LogP:2.31590
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:185.97926
Heavy Atom Count:9
Complexity:97.1

Purity/Quality:

98% ^*data from raw suppliers

5-Amino-2-bromo-3-picoline ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-41

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CN=C1Br)N
Uses 5-Amino-2-bromo-3-methylpyridine is a heterocyclic derivatives can be used as pharmaceutical intermediates.

Technology Process of 5-Amino-2-bromo-3-picoline

There total 2 articles about 5-Amino-2-bromo-3-picoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 23132-21-0
2-bromo-3-methyl-5-nitropyridine

: 38186-83-3
5-amino-2-bromo-3-methylpyridine

Guidance literature:: With iron; acetic acid; In water; at 40 ℃; for 1h;
DOI:10.1016/j.bmcl.2011.08.080

Reference yield:

: 38186-83-3
5-amino-2-bromo-3-methylpyridine

Guidance literature:: 2-Brom-3-methyl-5-nitropyridin (I), Sn, HCl;

Reference yield: 35.0%

: 38186-83-3
5-amino-2-bromo-3-methylpyridine

: 431-03-8
dimethylglyoxal

: 1-(6-bromo-5-methylpyridin-3-yl)ethanone

Guidance literature:: 5-amino-2-bromo-3-methylpyridine; With tetrafluoroboric acid; tert.-butylnitrite; In ethanol; water; at 0 - 20 ℃; for 1h; Schlenk technique; Inert atmosphere; Green chemistry;

dimethylglyoxal; In water; at 20 ℃; Inert atmosphere; Irradiation; Green chemistry;
DOI:10.1021/acs.joc.1c01290