1-chloro-4-nitro-7-(phenylmethoxy)-9(10H)-acridinone

Base Information

Chemical Name:1-chloro-4-nitro-7-(phenylmethoxy)-9(10H)-acridinone
CAS No.:99009-50-4
Molecular Formula:C₂₀H₁₃ClN₂O₄
Molecular Weight:380.787
Hs Code.:
DSSTox Substance ID:DTXSID801217618

Synonyms:1-chloro-4-nitro-7-(phenylmethoxy)-9(10H)-acridinone;SCHEMBL7064247;UTTSPNZJGMFEQW-UHFFFAOYSA-N;DTXSID801217618;99009-50-4;7-benzyloxy-1-chloro-4-nitroacridin-9(10H)-one;1-Chloro-4-nitro-7-(phenylmethoxy)-9-(10H)-acridinone

Suppliers and Price of 1-chloro-4-nitro-7-(phenylmethoxy)-9(10H)-acridinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-chloro-4-nitro-7-(phenylmethoxy)-9(10H)-acridinone

Chemical Property:

XLogP3:4.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:380.0563846
Heavy Atom Count:27
Complexity:563

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=CC3=C(C=C2)NC4=C(C=CC(=C4C3=O)Cl)[N+](=O)[O-]

Technology Process of 1-chloro-4-nitro-7-(phenylmethoxy)-9(10H)-acridinone

There total 4 articles about 1-chloro-4-nitro-7-(phenylmethoxy)-9(10H)-acridinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.3%

: 99009-51-5
2-Chloro-5-nitro-6-[[4-(phenylmethoxy)phenyl]amino]benzoic acid

: 99009-50-4
1-chloro-4-nitro-7-(phenylmethoxy)-9(10H)-acridinone

Guidance literature:: With N-ethyl-N,N-diisopropylamine; trichlorophosphate; In 1,2-dichloro-ethane; for 6h;
DOI:10.1016/j.bioorg.2021.105543

Reference yield:

: 6373-46-2
p-benzyloxyaniline

: 99009-50-4
1-chloro-4-nitro-7-(phenylmethoxy)-9(10H)-acridinone

Guidance literature:: Multi-step reaction with 2 steps

1: 47 percent / N,N-dimethylaniline, N,N-diisopropylethylamine / 18 h / Heating

2: 62 percent / N,N-dimethylaniline, POCl₃ / CHCl₃ / 1.5 h / Heating

With N,N-dimethyl-aniline; N-ethyl-N,N-diisopropylamine; trichlorophosphate; In chloroform;
DOI:10.1021/jm00104a001

Reference yield:

: 55775-97-8
2,6-dichloro-3-nitrobenzoic acid

: 99009-50-4
1-chloro-4-nitro-7-(phenylmethoxy)-9(10H)-acridinone

Guidance literature:: Multi-step reaction with 2 steps

1: 47 percent / N,N-dimethylaniline, N,N-diisopropylethylamine / 18 h / Heating

2: 62 percent / N,N-dimethylaniline, POCl₃ / CHCl₃ / 1.5 h / Heating

With N,N-dimethyl-aniline; N-ethyl-N,N-diisopropylamine; trichlorophosphate; In chloroform;
DOI:10.1021/jm00104a001