(R)-RuCl[(p-cymene)(BINAP)]Cl

Base Information

• Chemical Name: (R)-RuCl[(p-cymene)(BINAP)]Cl
• CAS No.: 130004-33-0
• Molecular Formula: C₅₄H₄₆ClP₂Ru*Cl
• Molecular Weight: 928.883
• Hs Code.: 28439000
• European Community (EC) Number: 631-328-8,664-469-9
• Mol file: 130004-33-0.mol

Synonyms:130004-33-0;145926-28-9;(R)-RuCl[(p-cymene)(BINAP)]Cl;(S)-RuCl[(p-cymene(BINAP)]Cl;Chloro[(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl](p-cymene)ruthenium(II) Chloride;(R)-(+)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHALENECHLORO(P-CYMENE)RUTHENIUM CHLORIDE;MFCD00134456;Chloro[(S)-(-)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl](p-cymene)ruthenium(II) chloride;dichlororuthenium;[1-(2-diphenylphosphanylnaphthalen-1-yl)naphthalen-2-yl]-diphenylphosphane;1-methyl-4-propan-2-ylbenzene;[2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene]chloro(p-cymene)ruthenium Chloride;[RuCl(p-cymene)((S)-binap)]Cl;[rucl((r)-binap)(p-cymene)]cl;AKOS015914587;SY071536;SY073011;D97679;F16612;A888798;[(S)-(-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene]chloro(p-cymene)ruthenium chloride, purum;Chloro[(R)-(+)-2,2 inverted exclamation mark -bis(diphenylphosphino)-1,1 inverted exclamation mark -binaphthyl](p-cymene)ruthenium(II) Chloride;Chloro[(S)-(-)-2,2 inverted exclamation mark -bis(diphenylphosphino)-1,1 inverted exclamation mark -binaphthyl](p-cymene)ruthenium(II) Chloride;CHLORO[(S)-(-)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL] (P-CYMENE)RUTHENIUM(II) CHLORIDE;Dichlororuthenium [1-(2-diphenylphosphanyl-1-naphthyl)-2-naphthyl]-diphenyl-phosphane 1-isopropyl-4-methylbenzene

Chemical Property of (R)-RuCl[(p-cymene)(BINAP)]Cl

Chemical Property:

• Appearance/Colour: Brown crystalline powder
• Melting Point: >100°C
• Boiling Point: 724.3 °C at 760 mmHg
• Flash Point: 419 °C
• PSA: 27.18000
• LogP: 13.67380
• Storage Temp.: Freezer (-20°C)
• Sensitive.: Air Sensitive
• Solubility.: Chloroform (Sparingly)
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 8
• Exact Mass: 928.149521
• Heavy Atom Count: 59
• Complexity: 886

Purity/Quality:

98%,99%, ^*data from raw suppliers

[2,2''-Bis(diphenylphosphino)-1,1''-binaphthalene]chloro(p-cymene)rutheniumChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)C(C)C.C1=CC=C(C=C1)P(C2=CC=CC=C2)C3=C(C4=CC=CC=C4C=C3)C5=C(C=CC6=CC=CC=C65)P(C7=CC=CC=C7)C8=CC=CC=C8.Cl[Ru]Cl
• Uses: Takasago Ligands and Complexes for Asymmetric Reactions

Technology Process of (R)-RuCl[(p-cymene)(BINAP)]Cl

There total 6 articles about (R)-RuCl[(p-cymene)(BINAP)]Cl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

[ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2 (52462-29-0) + 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl (76144-87-1,76189-55-4,76189-56-5,136655-44-2,98327-87-8) → (2,2'-bis(diphenylphosphino)-1,1'-binaphathalene)chloro(p-cymene)ruthenium chloride (130004-33-0,145926-28-9,376354-47-1)

Guidance literature:

In ethanol; dichloromethane; at 65 ℃; for 1.5h;

DOI:10.1002/chem.201605011

Reference yield: 94.0%

(S)-(-)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl + [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2 (52462-29-0) → ((-)-(1S)-[1,1'-binaphthalene]-2,2'-diylbis[diphenylphosphine-κP])chloro[(1,2,3,4,5,6-η)-1-methyl-4-(1-methylethyl)benzene]ruthenium(1+) chloride (376354-47-1,145926-28-9,130004-33-0)

Guidance literature:

Reference yield: 94.0%

(S)-(-)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl + dichloro(p-cymene)ruthenium(II) dimer → ((-)-(1S)-[1,1'-binaphthalene]-2,2'-diylbis[diphenylphosphine-κP])chloro[(1,2,3,4,5,6-η)-1-methyl-4-(1-methylethyl)benzene]ruthenium(1+) chloride (376354-47-1,145926-28-9,130004-33-0)

Guidance literature:

elem. anal.;

DOI:10.1039/c39890001208

upstream raw materials:

[ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂

2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl

(S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine)

Refernces

• 1、 -. "PROCESS FOR MAKING CGRP RECEPTOR ANTAGONIST". Page/Page column 67. . Retrieved 2011/02/24.
• 2、 -. "Asymmetric hydrogenation process". Page/Page column 8-9. . Retrieved 2008/06/13.