1-[4-(2,2':6',2''-TERPYRIDIN-4'-YL)PHENYL]METHANAMINE

Base Information

• Chemical Name: 1-[4-(2,2':6',2''-TERPYRIDIN-4'-YL)PHENYL]METHANAMINE
• CAS No.: 526196-33-8
• Molecular Formula: C22H18N4
• Molecular Weight: 338.41
• Mol file: 526196-33-8.mol

Synonyms:1-[4-(2,2':6',2''-Terpyridin-4'-yl)phenyl]methanamin;

Chemical Property of 1-[4-(2,2':6',2''-TERPYRIDIN-4'-YL)PHENYL]METHANAMINE

Chemical Property:

• Boiling Point: 524 °C at 760 mmHg
• Flash Point: 303.8 °C
• PSA: 64.69000
• Density: 1.187 g/cm³
• LogP: 5.03160

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-[4-(2,2':6',2''-TERPYRIDIN-4'-YL)PHENYL]METHANAMINE

There total 6 articles about 1-[4-(2,2':6',2''-TERPYRIDIN-4'-YL)PHENYL]METHANAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-({4-[6-(pyridin-2-yl)-[2,2'-bipyridin]-4-yl]phenyl}methyl)-2,3-dihydro-1H-isoindole-1,3-dione (526196-32-7) → 1-{4-[6-(pyridin-2-yl)-[2,2'-bipyridin]-4-yl]phenyl}methanamine (526196-33-8)

Guidance literature:

With hydrazine hydrate; In ethanol; chloroform; at 80 ℃; for 8h; Inert atmosphere;

Reference yield:

4'-(4-azidomethyl)phenyl-2,2':6',2''-terpyridine → 1-{4-[6-(pyridin-2-yl)-[2,2'-bipyridin]-4-yl]phenyl}methanamine (526196-33-8)

Guidance literature:

With triphenylphosphine; In methanol; for 2h; Reflux;

DOI:10.1039/c0cc03048a

Reference yield:

4-methyl-benzaldehyde (104-87-0) → 1-{4-[6-(pyridin-2-yl)-[2,2'-bipyridin]-4-yl]phenyl}methanamine (526196-33-8)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium hydroxide; ammonium hydroxide / ethanol / 12 h / 25 °C

2: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 8 h / 75 °C / Inert atmosphere

3: N,N-dimethyl-formamide / 5 h / 80 °C / Inert atmosphere

4: hydrazine hydrate / ethanol; chloroform / 8 h / 80 °C / Inert atmosphere

With ammonium hydroxide; N-Bromosuccinimide; hydrazine hydrate; sodium hydroxide; dibenzoyl peroxide; In tetrachloromethane; ethanol; chloroform; N,N-dimethyl-formamide;

upstream raw materials:

4-methyl-benzaldehyde

2-acetylpyridine

4'-(4-methylphenyl)-2,2':6',2-terpyridine

4'-(4-bromomethylphenyl)-2,2':6',2''-terpyridine

Downstream raw materials:

C₂₉H₂₉N₅O₄

C₃₇H₂₈N₄O₂

Refernces

• 1、 Zhang, Li-Yi,Zhang, Hua-Xin,Ye, Shen,Wen, Hui-Min,Chen, Zhong-Ning,Osawa, Masatoshi,Uosaki, Kohei,Sasaki, Yoichi. "A butadiyne-linked diruthenium molecular wire self-assembled on a gold electrode surface". supporting information; experimental part. p. 923 - 925. Retrieved 2011/03/17.