Cetrorelix acetate

Base Information

• Chemical Name: Cetrorelix acetate
• CAS No.: 130143-01-0
• Molecular Formula: C70H92ClN17O14.2(C2H4O2)
• Molecular Weight: 1551.16
• Mol file: 130143-01-0.mol

Synonyms:N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide diacetate

Chemical Property of Cetrorelix acetate

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 1768.4oC at 760 mmHg
• Flash Point: 1023.3oC
• PSA: 518.21000
• LogP: 6.72280
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

Cetrorelixacetate(1:2) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Clinical Use: Cetrorelix acetate is an analogue of GnRH with amino acid substitutions at residues 1, 2, 3, 6, and 10 and differing from ganirelix at amino acids 1, 6, and 8. Each of these substitutions are synthetic, non-DNA-directed amino acids and, like ganirelix acetate, impart GnRH antagonist activity to cetrorelix acetate. This drug also is marketed for use in women undergoing assisted reproductive therapy (ART) procedures, in which it is necessary to control their LH surge. This allows the follicles to develop to a size, as determined by ultrasound, that increases the success of timed insemination and oocyte retrieval for IVF. Like ganirelix acetate, cetrorelix acetate has an advantage over GnRH agonists, such as leuprolide acetate, because it reduces the fertility therapy cycle to days rather than weeks.