PIPERIDIN-3-ONE HYDROCHLORIDE

Base Information

• Chemical Name: PIPERIDIN-3-ONE HYDROCHLORIDE
• CAS No.: 61644-00-6
• Molecular Formula: C₅H₉NO*ClH
• Molecular Weight: 135.594
• Hs Code.: 2933399090
• Mol file: 61644-00-6.mol

Synonyms:3-Piperidinone,hydrochloride (9CI);

Chemical Property of PIPERIDIN-3-ONE HYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 0.0954mmHg at 25°C
• Boiling Point: 220 °C at 760 mmHg
• Flash Point: 86.8 °C
• PSA: 29.10000
• LogP: 1.06970
• Storage Temp.: Store at?0-5°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-PiperidinoneHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 37/38-41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3-Piperidinone Hydrochloride is a versatile synthetic building block used in various pharmaceutical preparations. 3-Piperidinone Hydrochloride is used as a reactant in the preparation of quinolines and quinazolines for treatment of benign prostatic hyperplasia.

Technology Process of PIPERIDIN-3-ONE HYDROCHLORIDE

There total 2 articles about PIPERIDIN-3-ONE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-oxo-piperidine-1-carboxylic acid tert-butyl ester (98977-36-7) → piperidin-3-one hydrochloride (61644-00-6)

Guidance literature:

With hydrogenchloride; In dichloromethane; ethyl acetate; at 20 ℃; for 1.5h;

Reference yield:

→ piperidin-3-one hydrochloride (61644-00-6)

Guidance literature:

upstream raw materials:

3-oxo-piperidine-1-carboxylic acid tert-butyl ester

Refernces

• 1、 -. "COMPOUNDS AS CRTH2 ANTAGONIST AND USES THEREOF". Paragraph 00457. . Retrieved 2016/04/20.
• 2、 -. "Lightening Agents and/or Dyes that Contain Aldehyde(s)". . . Retrieved 2010/12/29.