1L-1,2,4-tri-O-benzyl-3,5,6-tris-O-dibenzyloxyphosphoryl-myo-inositol

Base Information

• Chemical Name: 1L-1,2,4-tri-O-benzyl-3,5,6-tris-O-dibenzyloxyphosphoryl-myo-inositol
• CAS No.: 116907-55-2
• Molecular Formula: C₆₉H₆₉O₁₅P₃
• Molecular Weight: 1231.22
• Mol file: 116907-55-2.mol

Synonyms:1L-1,2,4-tri-O-benzyl-3,5,6-tris-O-dibenzyloxyphosphoryl-myo-inositol

Chemical Property of 1L-1,2,4-tri-O-benzyl-3,5,6-tris-O-dibenzyloxyphosphoryl-myo-inositol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1L-1,2,4-tri-O-benzyl-3,5,6-tris-O-dibenzyloxyphosphoryl-myo-inositol

There total 83 articles about 1L-1,2,4-tri-O-benzyl-3,5,6-tris-O-dibenzyloxyphosphoryl-myo-inositol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

dibenzyl [[bis(benzyloxy)phosphoryl]oxy]phosphonate (990-91-0) + (+/-)-2,5,6-tri-O-benzyl-myo-inositol (98906-30-0,104873-76-9,111466-07-0,114297-88-0,114297-91-5,114419-08-8,115184-71-9,115509-75-6,115509-76-7,118354-54-4,118354-55-5,128163-34-8,129706-80-5,136521-84-1,149713-88-2,149713-95-1) → DL-2,5,6-tri-O-benzyl-1,3,4-tris(dibenzylphospho)-myo-inositol (114342-70-0,114419-09-9,115184-72-0,115184-73-1,115510-57-1,115510-58-2,116907-55-2,118354-52-2,118396-24-0,129783-87-5)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃;

DOI:10.1016/S0040-4020(01)89510-7

Reference yield: 73.0%

Phosphorous acid dibenzyl ester (1R,2S,3S,4R,5R,6R)-2,3,6-tris-benzyloxy-4,5-bis-(bis-benzyloxy-phosphanyloxy)-cyclohexyl ester → DL-2,5,6-tri-O-benzyl-1,3,4-tris(dibenzylphospho)-myo-inositol (114342-70-0,114419-09-9,115184-72-0,115184-73-1,115510-57-1,115510-58-2,116907-55-2,118354-52-2,118396-24-0,129783-87-5)

Guidance literature:

With tert.-butylhydroperoxide; 1.) overnight, 2.) ethanol, RT, 15 min;

DOI:10.1021/jm00049a011

Reference yield: 72.0%

dibenzyl [[bis(benzyloxy)phosphoryl]oxy]phosphonate (990-91-0) + 2,3,6-tris-O-(phenylmethyl)-D-myo-inositol (104873-76-9) → 1L-1,2,4-tri-O-benzyl-3,5,6-tris-O-dibenzyloxyphosphoryl-myo-inositol (116907-55-2)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; at 0 ℃; for 1h;

upstream raw materials:

dibenzyl [[bis(benzyloxy)phosphoryl]oxy]phosphonate

(1R,2R,3S,4R,5R,6R)-3,5,6-Tris-benzyloxy-cyclohexane-1,2,4-triol

C₃₉H₅₄O₁₂

(±)-2,3,6-tri-O-benzyl-myo-inositol

Downstream raw materials:

(+/-)-myo-inositol-1,3,4-trisphosphate

1D-myo-inositol 1,4,5-tris(dihydrogen phosphat) sodium salt

D-myo-inositol 1,4,5-triphosphate

(+/-)-myo-inositol-2,4,5-trisphosphate