Technology Process of 2,6-dinitro-4-n-dodecylphenol
There total 1 articles about 2,6-dinitro-4-n-dodecylphenol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
nitric acid; acetic acid;
at 20 ℃;
for 3h;
Inert atmosphere;
DOI:10.1002/chem.201304161
- Guidance literature:
-
With
pyridine; trichlorophosphate;
for 2h;
Inert atmosphere;
Reflux;
DOI:10.1002/chem.201304161
- Guidance literature:
-
Multi-step reaction with 7 steps
1: trichlorophosphate; pyridine / 2 h / Inert atmosphere; Reflux
2: potassium fluoride; 18-crown-6 ether / tetrahydrofuran / 36 h / Reflux; Inert atmosphere
3: 5%-palladium/activated carbon; hydrogen / methanol / 24 h / 760.05 Torr / Inert atmosphere
4: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 12 h / 20 °C / Inert atmosphere
5: triethylamine / tetrahydrofuran / 2 h / 0 - 20 °C / Inert atmosphere
6: lithium hydroxide monohydrate; water / tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere
7: oxalyl dichloride; N,N-dimethyl-formamide / tetrahydrofuran / 0.5 h / -5 °C / Inert atmosphere
With
pyridine; dmap; potassium fluoride; oxalyl dichloride; 18-crown-6 ether; lithium hydroxide monohydrate; 5%-palladium/activated carbon; water; hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; N,N-dimethyl-formamide; trichlorophosphate;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1002/chem.201304161
