methyl (2S)-2-(tert-butoxycarbonylamino)-3-[4-(3,4,6-tri-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranosyloxy)phenyl]propionate

Base Information

Chemical Name:methyl (2S)-2-(tert-butoxycarbonylamino)-3-[4-(3,4,6-tri-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranosyloxy)phenyl]propionate
CAS No.:593260-81-2
Molecular Formula:C₄₂H₄₈N₂O₁₁
Molecular Weight:756.85
Hs Code.:

Synonyms:methyl (2S)-2-(tert-butoxycarbonylamino)-3-[4-(3,4,6-tri-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranosyloxy)phenyl]propionate

Suppliers and Price of methyl (2S)-2-(tert-butoxycarbonylamino)-3-[4-(3,4,6-tri-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranosyloxy)phenyl]propionate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl (2S)-2-(tert-butoxycarbonylamino)-3-[4-(3,4,6-tri-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranosyloxy)phenyl]propionate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl (2S)-2-(tert-butoxycarbonylamino)-3-[4-(3,4,6-tri-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranosyloxy)phenyl]propionate

There total 1 articles about methyl (2S)-2-(tert-butoxycarbonylamino)-3-[4-(3,4,6-tri-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranosyloxy)phenyl]propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 4326-36-7
(S)-N-(tert-butoxycarbonyl)tyrosine methyl ester

: 211621-55-5
3,4,6-tri-O-benzyl-2-nitro-D-galactal

: methyl (2S)-2-(tert-butoxycarbonylamino)-3-[4-(3,4,6-tri-O-benzyl-2-deoxy-2-nitro-β-D-galactopyranosyloxy)phenyl]propionate

: 593260-81-2
methyl (2S)-2-(tert-butoxycarbonylamino)-3-[4-(3,4,6-tri-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranosyloxy)phenyl]propionate

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; toluene; at 20 ℃; for 0.5h;
DOI:10.1002/ejoc.200200712

Reference yield: 88.0%

: 593260-81-2
methyl (2S)-2-(tert-butoxycarbonylamino)-3-[4-(3,4,6-tri-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranosyloxy)phenyl]propionate

: methyl (2S)-3-[4-(2-amino-3,4,6-tri-O-benzyl-2-deoxy-α-D-galactopyranosyloxy)phenyl]-2-(tert-butoxycarbonylamino)propionate

Guidance literature:: With hydrogen; Raney nickel T₄; In ethanol; at 20 ℃; for 48h;
DOI:10.1002/ejoc.200200712

Reference yield:

: 593260-81-2
methyl (2S)-2-(tert-butoxycarbonylamino)-3-[4-(3,4,6-tri-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranosyloxy)phenyl]propionate

: methyl O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-galactopyranosyl)-N-acetyl-L-tyrosinate

Guidance literature:: Multi-step reaction with 5 steps

1: 88 percent / hydrogen / Raney nickel T₄ / ethanol / 48 h / 20 °C

2: 87 percent / pyridine / 12 h / 20 °C

3: hydrogen / Pd/C (10percent) / methanol; acetic acid / 3 h

4: pyridine / 12 h / 20 °C

5: CF₃COOH / 12 h / 20 °C

With pyridine; hydrogen; trifluoroacetic acid; Raney nickel T₄; In methanol; ethanol; acetic acid;
DOI:10.1002/ejoc.200200712