2-(5-chloro-2-triphenylphosphoranylideneaminophenyl)-1,3-dioxane

Base Information

• Chemical Name: 2-(5-chloro-2-triphenylphosphoranylideneaminophenyl)-1,3-dioxane
• CAS No.: 1300044-01-2
• Molecular Formula: C₂₈H₂₅ClNO₂P
• Molecular Weight: 473.939
• Mol file: 1300044-01-2.mol

Synonyms:2-(5-chloro-2-triphenylphosphoranylideneaminophenyl)-1,3-dioxane

Chemical Property of 2-(5-chloro-2-triphenylphosphoranylideneaminophenyl)-1,3-dioxane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(5-chloro-2-triphenylphosphoranylideneaminophenyl)-1,3-dioxane

There total 2 articles about 2-(5-chloro-2-triphenylphosphoranylideneaminophenyl)-1,3-dioxane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2-(2-azido-5-chlorophenyl)-1,3-dioxane (1300044-03-4) + triphenylphosphine (603-35-0) → 2-(5-chloro-2-triphenylphosphoranylideneaminophenyl)-1,3-dioxane (1300044-01-2)

Guidance literature:

In diethyl ether; at 20 ℃; for 16h; Inert atmosphere;

DOI:10.1002/ejoc.201001372

Reference yield:

2-azido 5-chlorobenzaldehyde (916664-23-8) → 2-(5-chloro-2-triphenylphosphoranylideneaminophenyl)-1,3-dioxane (1300044-01-2)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid / benzene / 3 h / Reflux

2: diethyl ether / 16 h / 20 °C / Inert atmosphere

With toluene-4-sulfonic acid; In diethyl ether; benzene;

DOI:10.1002/ejoc.201001372

Reference yield: 92.0%

2-(5-chloro-2-triphenylphosphoranylideneaminophenyl)-1,3-dioxane (1300044-01-2) + diphenyl ketene (525-06-4) → 6'-chloro-3',3'-diphenylspiro[1,3-dioxane-2,4'(3'H)-quinoline] (1300044-16-9)

Guidance literature:

2-(5-chloro-2-triphenylphosphoranylideneaminophenyl)-1,3-dioxane; diphenyl ketene; In o-xylene; at 20 ℃; for 0.25h;

In o-xylene; Reflux;

DOI:10.1002/ejoc.201001372

upstream raw materials:

2-(2-azido-5-chlorophenyl)-1,3-dioxane

triphenylphosphine

2-azido 5-chlorobenzaldehyde

Downstream raw materials:

6'-chloro-3',3'-diphenylspiro[1,3-dioxane-2,4'(3'H)-quinoline]