1,6-Anhydro-2-O-benzyl-3,4-O-(1-methoxyethyliden)-β-D-galactopyranose

Base Information

• Chemical Name: 1,6-Anhydro-2-O-benzyl-3,4-O-(1-methoxyethyliden)-β-D-galactopyranose
• CAS No.: 76909-65-4
• Molecular Formula: C₁₆H₂₀O₆
• Molecular Weight: 308.331
• Mol file: 76909-65-4.mol

Synonyms:1,6-Anhydro-2-O-benzyl-3,4-O-(1-methoxyethyliden)-β-D-galactopyranose

Chemical Property of 1,6-Anhydro-2-O-benzyl-3,4-O-(1-methoxyethyliden)-β-D-galactopyranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,6-Anhydro-2-O-benzyl-3,4-O-(1-methoxyethyliden)-β-D-galactopyranose

There total 1 articles about 1,6-Anhydro-2-O-benzyl-3,4-O-(1-methoxyethyliden)-β-D-galactopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

Trimethyl orthoacetate (1445-45-0) + 1,6-anhydro-2-O-benzyl-β-D-galactopyranose (55287-63-3) → 1,6-Anhydro-2-O-benzyl-3,4-O-(1-methoxyethyliden)-β-D-galactopyranose (76909-65-4)

Guidance literature:

With toluene-4-sulfonic acid; In toluene;

Reference yield: 100.0%

1,6-Anhydro-2-O-benzyl-3,4-O-(1-methoxyethyliden)-β-D-galactopyranose (76909-65-4) → 3-O-Acetyl-1,6-anhydro-2-O-benzyl-β-D-galactopyranose (70056-64-3)

Guidance literature:

With water; acetic acid; for 0.0333333h;

Reference yield:

1,6-Anhydro-2-O-benzyl-3,4-O-(1-methoxyethyliden)-β-D-galactopyranose (76909-65-4) → 4-O-(2-Amino-6-O-acetyl-3,4-di-O-benzyl-2-desoxy-α-D-glucopyranosyl)-3-O-acetyl-1,6-anhydro-2-O-benzyl-β-D-galactopyranose

Guidance literature:

Multi-step reaction with 3 steps

1: 97 percent / 80percent aq. CH₃COOH

2: 1.) Ag₂CO₃, Drierite, 2.) AgClO₄ / 1.) CH₂Cl₂, 1 h, r.t. 2.) CH₂Cl₂, 3 h, 0 deg C; 3 h, r.t.

3: NaBH₄/NiCl₂*6H₂O / ethanol / 0.5 h / Ambient temperature

With calcium sulfate; sodium tetrahydroborate; silver perchlorate; acetic acid; silver carbonate; nickel dichloride; In ethanol;

upstream raw materials:

Trimethyl orthoacetate

1,6-anhydro-2-O-benzyl-β-D-galactopyranose

Downstream raw materials:

3-O-Acetyl-1,6-anhydro-2-O-benzyl-β-D-galactopyranose

4-O-(2-Acetamido-6-O-acetyl-3,4-di-O-benzyl-2-desoxy-α-D-glucopyranosyl)-3-O-acetyl-1,6-anhydro-2-O-benzyl-β-D-galactopyranose

4-O-(2-Acetamido-6-O-acetyl-3,4-di-O-benzyl-2-desoxy-α-D-glucopyranosyl)-1,3,6-tri-O-acetyl-2-O-benzyl-D-galactopyranose

1,3,6-Tri-O-acetyl-4-O-(6-O-acetyl-2-azido-3,4-di-O-benzyl-2-desoxy-α-D-glucopyranosyl)-2-O-benzyl-α-D-galactopyranose