N-(4-methoxyphenyl)-N'-(4-[(2-aminosulfonyl)phenyl]phenyl)maleamic amide

Base Information

Chemical Name:N-(4-methoxyphenyl)-N'-(4-[(2-aminosulfonyl)phenyl]phenyl)maleamic amide
CAS No.:330939-83-8
Molecular Formula:C₂₃H₂₁N₃O₅S
Molecular Weight:451.503
Hs Code.:

Synonyms:N-(4-methoxyphenyl)-N'-(4-[(2-aminosulfonyl)phenyl]phenyl)maleamic amide

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Chemical Property of N-(4-methoxyphenyl)-N'-(4-[(2-aminosulfonyl)phenyl]phenyl)maleamic amide

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Technology Process of N-(4-methoxyphenyl)-N'-(4-[(2-aminosulfonyl)phenyl]phenyl)maleamic amide

There total 2 articles about N-(4-methoxyphenyl)-N'-(4-[(2-aminosulfonyl)phenyl]phenyl)maleamic amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 330942-89-7
N-(4-methoxyphenyl)-N'-(4-[(2-tert-butylaminosulfonyl)phenyl]phenyl)maleamic amide

: 330939-83-8
N-(4-methoxyphenyl)-N'-(4-[(2-aminosulfonyl)phenyl]phenyl)maleamic amide

Guidance literature:: With trifluoroacetic acid; at 20 ℃;

Reference yield:

: 24870-10-8
N-(4-methoxyphenyl)maleamic acid

: 193006-34-7
4-(2'-tert-butylaminosulfonylphenyl)aniline

: 330939-83-8
N-(4-methoxyphenyl)-N'-(4-[(2-aminosulfonyl)phenyl]phenyl)maleamic amide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate / N,N-dimethyl-formamide / 20 °C

2: trifluoroacetic acid / 20 °C

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; trifluoroacetic acid; In N,N-dimethyl-formamide;