Benzyl 3-aminopiperidine-1-carboxylate

Base Information

Chemical Name:Benzyl 3-aminopiperidine-1-carboxylate
CAS No.:711002-74-3
Molecular Formula:C13H18N2O2
Molecular Weight:234.298
Hs Code.:29333990
European Community (EC) Number:674-642-0
DSSTox Substance ID:DTXSID601258438
Mol file:711002-74-3.mol

Synonyms:711002-74-3;3-AMINO-1-N-CBZ-PIPERIDINE;Benzyl 3-aminopiperidine-1-carboxylate;1-N-Cbz-3-aminopiperidine;BENZYL-3-AMINOPIPERIDINE-1-CARBOXYLATE;3-amino-piperidine-1-carboxylic acid benzyl ester;1-PIPERIDINECARBOXYLIC ACID, 3-AMINO-, PHENYLMETHYL ESTER;MFCD03001672;MFCD05864625;3-Amino-1-benzyloxycarbonyl piperidine;1-Cbz-piperidin-3-amine;SCHEMBL654999;3-Amino-1-N-Fmoc-piperidine;AMY5282;DL-3-Amino-1-N-Cbz-piperidine;PBFBPDLWODIXHK-UHFFFAOYSA-N;(3S)-3-Amino-1-Cbz-piperidine;DTXSID601258438;1-benzyloxycarbonyl-3-aminopiperidine;3-Aminopiperidine, N1-CBZ protected;AKOS005146163;FS-1272;PB21885;PB25014;PB29216;SB10256;SB10257;3-amino-1-N-cbz-piperidine, AldrichCPR;SY033486;SY064428;(S)-N-CARBOBENZYLOXYCYCLOHEXYLALANINOL;A9336;CS-0041748;FT-0603859;FT-0630230;FT-0659190;Phenylmethyl 3-amino-1-piperidinecarboxylate;3-Amino-1-N-Cbz-piperidine 711002-74-3;3-aminopiperidine-1-carboxylic acid benzyl ester;J-505025;3-Amino-piperidine-1-carboxylic acid benzyl ester

Suppliers and Price of Benzyl 3-aminopiperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Benzyl3-Aminopiperidine-1-carboxylate
50mg
$ 60.00

SynQuest Laboratories
3-Aminopiperidine, N1-Cbz protected 97%
1 g
$ 88.00

SynQuest Laboratories
3-Aminopiperidine, N1-Cbz protected 97%
25 g
$ 500.00

SynQuest Laboratories
3-Aminopiperidine, N1-Cbz protected 97%
5 g
$ 145.00

Matrix Scientific
3-Amino-1-N-Cbz-piperidine 95+%
25g
$ 274.00

Matrix Scientific
3-Amino-1-N-Cbz-piperidine 95+%
5g
$ 85.00

Matrix Scientific
3-Amino-1-N-Cbz-piperidine 95+%
100g
$ 868.00

Labseeker
3-Amino-1-N-Cbz-piperidine 96
5g
$ 850.00

J&W Pharmlab
3-Amino-piperidine-1-carboxylicacidbenzylester 96%
5g
$ 88.00

Biosynth Carbosynth
3-Aminopiperidine-1-carboxylic acid benzyl ester
100 g
$ 850.00

Total 50 raw suppliers

Chemical Property of Benzyl 3-aminopiperidine-1-carboxylate

Chemical Property:

Vapor Pressure:1.38E-05mmHg at 25°C
Melting Point:168-170 °C
Refractive Index:1.558
Boiling Point:367.2 °C at 760 mmHg
PKA:10.33±0.20(Predicted)
Flash Point:175.9 °C
PSA：55.56000
Density:1.151 g/cm³
LogP:2.38450
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:234.136827821
Heavy Atom Count:17
Complexity:252

Purity/Quality:

99%, ^*data from raw suppliers

Benzyl3-Aminopiperidine-1-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(CN(C1)C(=O)OCC2=CC=CC=C2)N

Technology Process of Benzyl 3-aminopiperidine-1-carboxylate

There total 3 articles about Benzyl 3-aminopiperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 68471-58-9
1-(benzyloxycarbonyl)-1,2,3,4-tetrahydropyridine

: 711002-74-3
(RS)-benzyl 3-aminopiperidine-1-carboxylate

Guidance literature:: With iridium(lll) bis[2-(2,4-difluorophenyl)-5-methylpyridine-N,C₂₀]-4,40-di-tert-butyl-2,20-bipyridine hexafluorophosphate; 2,4,6-Triisopropylthiophenol; ammonia; In methanol; toluene; at 20 ℃; for 16h; regioselective reaction; Inert atmosphere; Irradiation;
DOI:10.1002/chem.202003562

Reference yield:

: 406213-47-6
3-t-butoxycarbonylaminopiperidin-1-carboxylic acid benzyl ester

: 711002-74-3
(RS)-benzyl 3-aminopiperidine-1-carboxylate

Guidance literature:: 3-t-butoxycarbonylaminopiperidin-1-carboxylic acid benzyl ester; With hydrogenchloride; In 1,4-dioxane; at 0 - 20 ℃;

With water; sodium carbonate;

Reference yield:

: 3742-91-4
N-(benzyloxycarbonyl)piperidine

: 711002-74-3
(RS)-benzyl 3-aminopiperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: lithium nitrate; copper diacetate; 3,6‐di‐tert‐butyl‐9‐mesityl‐10‐phenylacridin‐10‐ium tetrafluoroborate / acetonitrile / Irradiation; Inert atmosphere

2: 3,6‐di‐tert‐butyl‐9‐mesityl‐10‐phenylacridin‐10‐ium tetrafluoroborate; thiophenol; sodium acetate; ammonium carbamate / 1,2-dichloro-ethane / Inert atmosphere; Irradiation

With 3,6‐di‐tert‐butyl‐9‐mesityl‐10‐phenylacridin‐10‐ium tetrafluoroborate; lithium nitrate; copper diacetate; sodium acetate; ammonium carbamate; thiophenol; In 1,2-dichloro-ethane; acetonitrile;
DOI:10.1021/acscatal.1c00099