1-oxyl-2,2,6,6-tetramethyl-piperidine-4-carboxylic acid[(2-(3,4-dimethoxyphenyl))-5-[[2-(3,4-dimethoxyphenyl)-ethyl]methylamino]-2-isopropyl]-pentylamide radical

Base Information

• Chemical Name: 1-oxyl-2,2,6,6-tetramethyl-piperidine-4-carboxylic acid[(2-(3,4-dimethoxyphenyl))-5-[[2-(3,4-dimethoxyphenyl)-ethyl]methylamino]-2-isopropyl]-pentylamide radical
• CAS No.: 1228254-15-6
• Molecular Formula: C₃₇H₅₈N₃O₆
• Molecular Weight: 640.884
• Mol file: 1228254-15-6.mol

Synonyms:1-oxyl-2,2,6,6-tetramethyl-piperidine-4-carboxylic acid[(2-(3,4-dimethoxyphenyl))-5-[[2-(3,4-dimethoxyphenyl)-ethyl]methylamino]-2-isopropyl]-pentylamide radical

Chemical Property of 1-oxyl-2,2,6,6-tetramethyl-piperidine-4-carboxylic acid[(2-(3,4-dimethoxyphenyl))-5-[[2-(3,4-dimethoxyphenyl)-ethyl]methylamino]-2-isopropyl]-pentylamide radical

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-oxyl-2,2,6,6-tetramethyl-piperidine-4-carboxylic acid[(2-(3,4-dimethoxyphenyl))-5-[[2-(3,4-dimethoxyphenyl)-ethyl]methylamino]-2-isopropyl]-pentylamide radical

There total 1 articles about 1-oxyl-2,2,6,6-tetramethyl-piperidine-4-carboxylic acid[(2-(3,4-dimethoxyphenyl))-5-[[2-(3,4-dimethoxyphenyl)-ethyl]methylamino]-2-isopropyl]-pentylamide radical which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

1-oxyl-4-carboxyl-2,2,6,6-tetramethylpiperidine (37149-18-1) + (+/-)-5-<(3,4-dimethoxyphenethyl)methylamino>-2-(3,4-dimethoxyphenyl)-2-isopropylpentylamine (102852-52-8) → 1-oxyl-2,2,6,6-tetramethyl-piperidine-4-carboxylic acid[(2-(3,4-dimethoxyphenyl))-5-[[2-(3,4-dimethoxyphenyl)-ethyl]methylamino]-2-isopropyl]-pentylamide radical (1228254-15-6)

Guidance literature:

1-oxyl-4-carboxyl-2,2,6,6-tetramethylpiperidine; (+/-)-5-<(3,4-dimethoxyphenethyl)methylamino>-2-(3,4-dimethoxyphenyl)-2-isopropylpentylamine; With dmap; In ethyl acetate; at 20 ℃; for 0.166667h;

With dicyclohexyl-carbodiimide; In ethyl acetate; at 20 ℃; for 24h;

DOI:10.1016/j.bmc.2010.02.040

Reference yield: 60.0%

1-oxyl-2,2,6,6-tetramethyl-piperidine-4-carboxylic acid[(2-(3,4-dimethoxyphenyl))-5-[[2-(3,4-dimethoxyphenyl)-ethyl]methylamino]-2-isopropyl]-pentylamide radical (1228254-15-6) → 1-hydroxy-2,2,6,6-tetramethyl-piperidine-4-carboxylicacid-[(2-(3,4-dimethoxyphenyl))-5-[[2-(3,4-dimethoxy-phenyl)ethyl]-methyl-amino]-2-isopropyl]-pentyl-amide hydrochloride

Guidance literature:

With hydrogenchloride; In ethanol; for 0.333333h; Reflux;

DOI:10.1016/j.bmc.2010.02.040

Reference yield:

1-oxyl-2,2,6,6-tetramethyl-piperidine-4-carboxylic acid[(2-(3,4-dimethoxyphenyl))-5-[[2-(3,4-dimethoxyphenyl)-ethyl]methylamino]-2-isopropyl]-pentylamide radical (1228254-15-6) → C37H59N3O5

Guidance literature:

1-oxyl-2,2,6,6-tetramethyl-piperidine-4-carboxylic acid[(2-(3,4-dimethoxyphenyl))-5-[[2-(3,4-dimethoxyphenyl)-ethyl]methylamino]-2-isopropyl]-pentylamide radical; With iron; acetic acid; at 20 - 70 ℃;

With potassium carbonate; In water; pH=9;

DOI:10.1016/j.bmc.2010.02.040

upstream raw materials:

1-oxyl-4-carboxyl-2,2,6,6-tetramethylpiperidine

(+/-)-5-<(3,4-dimethoxyphenethyl)methylamino>-2-(3,4-dimethoxyphenyl)-2-isopropylpentylamine

Refernces