C₂₆H₃₄FN₃O₄

Base Information

• Chemical Name: C₂₆H₃₄FN₃O₄
• CAS No.: 1587701-26-5
• Molecular Formula: C₂₆H₃₄FN₃O₄
• Molecular Weight: 471.572
• Mol file: 1587701-26-5.mol

Synonyms:C₂₆H₃₄FN₃O₄

Chemical Property of C₂₆H₃₄FN₃O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₃₄FN₃O₄

There total 8 articles about C₂₆H₃₄FN₃O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C16H18FN3 (1432481-30-5) + isobutyl chloroformate (543-27-1) → C26H34FN3O4 (1587701-26-5)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; at 20 ℃;

DOI:10.1038/aps.2013.79

Reference yield:

4-fluorobenzaldehyde (459-57-4) → C26H34FN3O4 (1587701-26-5)

Guidance literature:

Multi-step reaction with 7 steps

1: toluene-4-sulfonic acid / toluene / 3 h / Reflux

2: sodium tetrahydroborate / 1,4-dioxane; methanol / 2 h / 20 °C

3: hydrogen / methanol / 3 h / 20 °C / 760.05 Torr

4: sodium hydrogencarbonate / tetrahydrofuran; water / 20 °C

5: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2 h / 60 °C

6: trifluoroacetic acid / dichloromethane / 2 h / 60 °C

7: N-ethyl-N,N-diisopropylamine / 1,4-dioxane / 20 °C

With sodium tetrahydroborate; hydrogen; sodium hydrogencarbonate; toluene-4-sulfonic acid; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; N,N-dimethyl-formamide; toluene;

DOI:10.1038/aps.2013.79

Reference yield:

2-nitro-1,4-phenylenediamine (5307-14-2,183870-67-9) → C26H34FN3O4 (1587701-26-5)

Guidance literature:

Multi-step reaction with 7 steps

1: toluene-4-sulfonic acid / toluene / 3 h / Reflux

2: sodium tetrahydroborate / 1,4-dioxane; methanol / 2 h / 20 °C

3: hydrogen / methanol / 3 h / 20 °C / 760.05 Torr

4: sodium hydrogencarbonate / tetrahydrofuran; water / 20 °C

5: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2 h / 60 °C

6: trifluoroacetic acid / dichloromethane / 2 h / 60 °C

7: N-ethyl-N,N-diisopropylamine / 1,4-dioxane / 20 °C

With sodium tetrahydroborate; hydrogen; sodium hydrogencarbonate; toluene-4-sulfonic acid; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; N,N-dimethyl-formamide; toluene;

DOI:10.1038/aps.2013.79

upstream raw materials:

2-nitro-1,4-phenylenediamine

4-fluorobenzaldehyde

2-amino-5-(4-fluorobenzylideneamino)nitrobenzene

C₁₆H₁₈FN₃