Technology Process of C21H26O3S
There total 4 articles about C21H26O3S which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
diiodomethane;
With
diethylzinc;
In
1,2-dimethoxyethane; hexane; dichloromethane;
at 0 ℃;
for 0.916667h;
Inert atmosphere;
C20H24O3S;
In
1,2-dimethoxyethane; hexane; dichloromethane;
at 20 ℃;
Inert atmosphere;
Cooling;
With
hydrogenchloride; ammonium chloride;
In
1,2-dimethoxyethane; hexane; dichloromethane; water;
diastereospecific reaction;
DOI:10.1021/jo1019909
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: zinc(II) chloride / tetrahydrofuran / 0.5 h / 20 °C
1.2: 1 h / -78 °C / Inert atmosphere
1.3: 20 °C / pH 2
2.1: diethylzinc / 1,2-dimethoxyethane; hexane; dichloromethane / 0.92 h / 0 °C / Inert atmosphere
2.2: 20 °C / Inert atmosphere; Cooling
With
diethylzinc; zinc(II) chloride;
In
tetrahydrofuran; 1,2-dimethoxyethane; hexane; dichloromethane;
DOI:10.1021/jo1019909
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: toluene / 24 h / Reflux
2.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 0.5 h / -40 °C / Inert atmosphere
2.2: 1 h / 0 °C / Inert atmosphere
2.3: pH 2
3.1: zinc(II) chloride / tetrahydrofuran / 0.5 h / 20 °C
3.2: 1 h / -78 °C / Inert atmosphere
3.3: 20 °C / pH 2
4.1: diethylzinc / 1,2-dimethoxyethane; hexane; dichloromethane / 0.92 h / 0 °C / Inert atmosphere
4.2: 20 °C / Inert atmosphere; Cooling
With
diethylzinc; zinc(II) chloride; lithium diisopropyl amide;
In
tetrahydrofuran; 1,2-dimethoxyethane; hexane; dichloromethane; toluene;
DOI:10.1021/jo1019909
