{(2S,3S)-3-[(R)-1,2-Bis-(tert-butyl-diphenyl-silanyloxy)-ethyl]-oxiranyl}-methanol

Base Information

Chemical Name:{(2S,3S)-3-[(R)-1,2-Bis-(tert-butyl-diphenyl-silanyloxy)-ethyl]-oxiranyl}-methanol
CAS No.:404830-01-9
Molecular Formula:C₃₇H₄₆O₄Si₂
Molecular Weight:610.941
Hs Code.:

Synonyms:{(2S,3S)-3-[(R)-1,2-Bis-(tert-butyl-diphenyl-silanyloxy)-ethyl]-oxiranyl}-methanol

Suppliers and Price of {(2S,3S)-3-[(R)-1,2-Bis-(tert-butyl-diphenyl-silanyloxy)-ethyl]-oxiranyl}-methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of {(2S,3S)-3-[(R)-1,2-Bis-(tert-butyl-diphenyl-silanyloxy)-ethyl]-oxiranyl}-methanol

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of {(2S,3S)-3-[(R)-1,2-Bis-(tert-butyl-diphenyl-silanyloxy)-ethyl]-oxiranyl}-methanol

There total 10 articles about {(2S,3S)-3-[(R)-1,2-Bis-(tert-butyl-diphenyl-silanyloxy)-ethyl]-oxiranyl}-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 404829-91-0
Acetic acid (Z)-(S)-4,5-bis-(tert-butyl-diphenyl-silanyloxy)-pent-2-enyl ester

: 404829-93-2
{(2R,3R)-3-[(R)-1,2-Bis-(tert-butyl-diphenyl-silanyloxy)-ethyl]-oxiranyl}-methanol

: 404830-01-9
{(2S,3S)-3-[(R)-1,2-Bis-(tert-butyl-diphenyl-silanyloxy)-ethyl]-oxiranyl}-methanol

Guidance literature:: With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 - 20 ℃;
DOI:10.1055/s-2001-18742

Reference yield:

: (Z)-(S)-4,5-Bis-(tert-butyl-diphenyl-silanyloxy)-pent-2-en-1-ol

: 404829-93-2
{(2R,3R)-3-[(R)-1,2-Bis-(tert-butyl-diphenyl-silanyloxy)-ethyl]-oxiranyl}-methanol

: 404830-01-9
{(2S,3S)-3-[(R)-1,2-Bis-(tert-butyl-diphenyl-silanyloxy)-ethyl]-oxiranyl}-methanol

Guidance literature:: With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 - 20 ℃;
DOI:10.1002/ejoc.200390108

Reference yield:

: 91926-90-8,917877-01-1
ethyl (Z)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)acrylate

: 404830-01-9
{(2S,3S)-3-[(R)-1,2-Bis-(tert-butyl-diphenyl-silanyloxy)-ethyl]-oxiranyl}-methanol

Guidance literature:: Multi-step reaction with 6 steps

1: 80 percent / DIBAL-H / CH₂Cl₂ / 4 h / 0 °C

2: 99 percent / DMAP / CH₂Cl₂ / 1 h / 20 °C

3: 85 percent / HCl / H₂O; acetonitrile / 2.5 h / 0 °C

4: 70 percent / imidazole / CH₂Cl₂ / 2 h / 20 °C

5: KOH / methanol / 0.5 h / 20 °C

6: mCPBA; NaHCO₃ / CH₂Cl₂ / 0 - 20 °C

With 1H-imidazole; hydrogenchloride; dmap; potassium hydroxide; diisobutylaluminium hydride; sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In methanol; dichloromethane; water; acetonitrile;
DOI:10.1002/ejoc.200390108