(1R,2S)-1-[(2S)-(N-Cbz-L-alanylamino)-3-butenyl]-2-{[(2R,3S)-3-((2S)-2-methylpropyl)-4-oxooxetan-2-yl]carbonylamino}cyclopopane

Base Information

• Chemical Name: (1R,2S)-1-[(2S)-(N-Cbz-L-alanylamino)-3-butenyl]-2-{[(2R,3S)-3-((2S)-2-methylpropyl)-4-oxooxetan-2-yl]carbonylamino}cyclopopane
• CAS No.: 1013331-16-2
• Molecular Formula: C₂₆H₃₅N₃O₆
• Molecular Weight: 485.58
• Mol file: 1013331-16-2.mol

Synonyms:(1R,2S)-1-[(2S)-(N-Cbz-L-alanylamino)-3-butenyl]-2-{[(2R,3S)-3-((2S)-2-methylpropyl)-4-oxooxetan-2-yl]carbonylamino}cyclopopane

Chemical Property of (1R,2S)-1-[(2S)-(N-Cbz-L-alanylamino)-3-butenyl]-2-{[(2R,3S)-3-((2S)-2-methylpropyl)-4-oxooxetan-2-yl]carbonylamino}cyclopopane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (1R,2S)-1-[(2S)-(N-Cbz-L-alanylamino)-3-butenyl]-2-{[(2R,3S)-3-((2S)-2-methylpropyl)-4-oxooxetan-2-yl]carbonylamino}cyclopopane

There total 1 articles about (1R,2S)-1-[(2S)-(N-Cbz-L-alanylamino)-3-butenyl]-2-{[(2R,3S)-3-((2S)-2-methylpropyl)-4-oxooxetan-2-yl]carbonylamino}cyclopopane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C13H20O5 (1013331-17-3) + C18H25N3O3 (1160835-26-6) → (1R,2S)-1-[(2S)-(N-Cbz-L-alanylamino)-3-butenyl]-2-{[(2R,3S)-3-((2S)-2-methylpropyl)-4-oxooxetan-2-yl]carbonylamino}cyclopopane (1013331-16-2)

Guidance literature:

With sodium hydrogencarbonate; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 17h;

DOI:10.1021/ol8013304

Reference yield:

(1R,2S)-1-[(2S)-(N-Cbz-L-alanylamino)-3-butenyl]-2-{[(2R,3S)-3-((2S)-2-methylpropyl)-4-oxooxetan-2-yl]carbonylamino}cyclopopane (1013331-16-2) → N-Cbz-belactosin A (692778-52-2)

Guidance literature:

With potassium permanganate; sodium periodate; sodium hydrogencarbonate; In water; acetone; at 20 ℃; for 17h;

DOI:10.1021/ol8013304

upstream raw materials:

C₁₃H₂₀O₅

C₁₈H₂₅N₃O₃

Downstream raw materials:

N-Cbz-belactosin A